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• W4297341504 abstract "Abstract Objective To investigate the independent risk factors for the first recurrence after endovascular management in patients with Budd-Chiari syndrome (BCS), and to establish a prediction model for predicting recurrence in target patients. Methods BCS patients who underwent endovascular treatment in the Affiliated Hospital of Xuzhou Medical University from January 2010 to December 2015 were retrospectively examined, with their clinical, laboratory test, and imaging data collected and analyzed. Independent risk factors for recurrence were identified, and a prediction model was established and validated. Results A total of 450 patients met the filtering criteria, and 102 patients recurred during the follow-up. The median follow-up time was 87 months, ranging from 1 to 137 months. The 1-, 3-, 5- and 10-year cumulative recurrence rate was 9.11% (6.41%-11.73%), 17.35% (13.77%-20.78%), 20.10% (16.30%-23.72%), and 23.06% (18.86%-27.04%), respectively. Liver cirrhosis, ascites, thrombosis, and obstructed HV + AHV (all three main HVs and AHVs obstruct) are independent risk factors, while age is an independent protective factor. The risk score = (-0.385981 * Age/10)་(0.0404184 * PT)་(0.0943423 * CRE/10)་(0.0157053 * LDH/10)་(0.592179 * LC)་(0.896034 * Ascite)་(0.691346 * Thrombosis)་(0.886741 * (HV + AHV)). A nomogram was provided for better clinical application. Patients with a risk score < 1.57 were stratified as the low-risk group while those ≥ 1.57 as the high-risk group ( P < 0.001). Conclusion Liver cirrhosis, ascites, thrombosis, and obstructed HV + AHV are independent risk factors for the first recurrence, age is an independent protective factor. The prediction model can effectively and conveniently predict the risk of recurrence and screen out patients at a high recurrence risk." @default.
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• W4297341504 date "2022-09-27" @default.
• W4297341504 modified "2023-10-18" @default.
• W4297341504 title "Establishment and validation of a prediction model for the first recurrence of Budd-Chiari syndrome after endovascular treatment: A large sample size, single-center retrospective study" @default.
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• W4297341504 doi "https://doi.org/10.21203/rs.3.rs-2073408/v1" @default.
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