Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297380485> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W4297380485 abstract "Pulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease that negatively impacts health-related quality of life (HRQOL). The PAH-symptoms and impact (PAH-SYMPACT) questionnaire is a validated disease-specific patient-reported outcome (PRO) instrument that assesses a patient's symptoms and the impact of PAH and its treatment on well-being. We performed a single-center prospective cohort study of patients with PAH to determine the feasibility of assessing PROs in clinical practice and to determine the association between PAH-SYMPACT domains and clinical characteristics and outcomes. One hundred and ten patients completed the 1-day version of the PAH-SYMPACT questionnaire which consists of 22 Likert-scale questions that assess HRQOL across four domains: cardiopulmonary (CP) symptoms, cardiovascular (CV) symptoms, physical impact (PI), and cognitive and emotional (CE) impact. Higher scores indicate worse HRQOL. Patients were predominantly female (n = 86, 78%) with a mean age of 57.8 ± 16.2 years. While several patient characteristics were associated with CP and PI domains, few were associated with CV and CE domains. PI and CE impact scores were associated with recent hospitalizations and mortality and CE impact score was independently associated with an increased risk of death after adjustment for disease severity (hazard ratio: 3.29, 95% confidence interval: 1.56–6.91, p = 0.002). In conclusion, the assessment of PROs in clinical practice using the PAH-SYMPACT questionnaire is both feasible and valuable. PAH-SYMPACT scores have independent prognostic value and are not adequately reflected by traditional measures of disease severity. These findings underscore the importance of assessing HRQOL in clinical practice." @default.
- W4297380485 created "2022-09-28" @default.
- W4297380485 creator A5002229961 @default.
- W4297380485 creator A5010482795 @default.
- W4297380485 creator A5016679095 @default.
- W4297380485 creator A5024460976 @default.
- W4297380485 creator A5031317277 @default.
- W4297380485 creator A5036732236 @default.
- W4297380485 creator A5040246998 @default.
- W4297380485 creator A5041429798 @default.
- W4297380485 creator A5046324516 @default.
- W4297380485 creator A5051289606 @default.
- W4297380485 creator A5078732560 @default.
- W4297380485 creator A5081475141 @default.
- W4297380485 creator A5082883953 @default.
- W4297380485 date "2022-10-01" @default.
- W4297380485 modified "2023-10-08" @default.
- W4297380485 title "The feasibility and value of assessing patient‐reported outcomes in pulmonary arterial hypertension" @default.
- W4297380485 cites W2106484781 @default.
- W4297380485 cites W2154332638 @default.
- W4297380485 cites W2246544686 @default.
- W4297380485 cites W2421336374 @default.
- W4297380485 cites W2802193200 @default.
- W4297380485 cites W2903775115 @default.
- W4297380485 cites W2904385559 @default.
- W4297380485 cites W2904463477 @default.
- W4297380485 cites W2911099424 @default.
- W4297380485 cites W2911671206 @default.
- W4297380485 cites W3016774958 @default.
- W4297380485 cites W3040198940 @default.
- W4297380485 doi "https://doi.org/10.1002/pul2.12143" @default.
- W4297380485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36262468" @default.
- W4297380485 hasPublicationYear "2022" @default.
- W4297380485 type Work @default.
- W4297380485 citedByCount "1" @default.
- W4297380485 countsByYear W42973804852022 @default.
- W4297380485 crossrefType "journal-article" @default.
- W4297380485 hasAuthorship W4297380485A5002229961 @default.
- W4297380485 hasAuthorship W4297380485A5010482795 @default.
- W4297380485 hasAuthorship W4297380485A5016679095 @default.
- W4297380485 hasAuthorship W4297380485A5024460976 @default.
- W4297380485 hasAuthorship W4297380485A5031317277 @default.
- W4297380485 hasAuthorship W4297380485A5036732236 @default.
- W4297380485 hasAuthorship W4297380485A5040246998 @default.
- W4297380485 hasAuthorship W4297380485A5041429798 @default.
- W4297380485 hasAuthorship W4297380485A5046324516 @default.
- W4297380485 hasAuthorship W4297380485A5051289606 @default.
- W4297380485 hasAuthorship W4297380485A5078732560 @default.
- W4297380485 hasAuthorship W4297380485A5081475141 @default.
- W4297380485 hasAuthorship W4297380485A5082883953 @default.
- W4297380485 hasBestOaLocation W42973804852 @default.
- W4297380485 hasConcept C126322002 @default.
- W4297380485 hasConcept C159110408 @default.
- W4297380485 hasConcept C1862650 @default.
- W4297380485 hasConcept C188816634 @default.
- W4297380485 hasConcept C201903717 @default.
- W4297380485 hasConcept C207103383 @default.
- W4297380485 hasConcept C2779134260 @default.
- W4297380485 hasConcept C2779951463 @default.
- W4297380485 hasConcept C44249647 @default.
- W4297380485 hasConcept C71924100 @default.
- W4297380485 hasConcept C72563966 @default.
- W4297380485 hasConceptScore W4297380485C126322002 @default.
- W4297380485 hasConceptScore W4297380485C159110408 @default.
- W4297380485 hasConceptScore W4297380485C1862650 @default.
- W4297380485 hasConceptScore W4297380485C188816634 @default.
- W4297380485 hasConceptScore W4297380485C201903717 @default.
- W4297380485 hasConceptScore W4297380485C207103383 @default.
- W4297380485 hasConceptScore W4297380485C2779134260 @default.
- W4297380485 hasConceptScore W4297380485C2779951463 @default.
- W4297380485 hasConceptScore W4297380485C44249647 @default.
- W4297380485 hasConceptScore W4297380485C71924100 @default.
- W4297380485 hasConceptScore W4297380485C72563966 @default.
- W4297380485 hasFunder F4320306143 @default.
- W4297380485 hasIssue "4" @default.
- W4297380485 hasLocation W42973804851 @default.
- W4297380485 hasLocation W42973804852 @default.
- W4297380485 hasLocation W42973804853 @default.
- W4297380485 hasOpenAccess W4297380485 @default.
- W4297380485 hasPrimaryLocation W42973804851 @default.
- W4297380485 hasRelatedWork W1516595110 @default.
- W4297380485 hasRelatedWork W1548660409 @default.
- W4297380485 hasRelatedWork W1973635299 @default.
- W4297380485 hasRelatedWork W2028861440 @default.
- W4297380485 hasRelatedWork W2086685588 @default.
- W4297380485 hasRelatedWork W2490521022 @default.
- W4297380485 hasRelatedWork W2590492472 @default.
- W4297380485 hasRelatedWork W2760462550 @default.
- W4297380485 hasRelatedWork W2809220925 @default.
- W4297380485 hasRelatedWork W2947904584 @default.
- W4297380485 hasVolume "12" @default.
- W4297380485 isParatext "false" @default.
- W4297380485 isRetracted "false" @default.
- W4297380485 workType "article" @default.