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- W4297382026 abstract "Chirinos et al.1 demonstrated that endotrophin levels are strongly associated with all-cause mortality and a composite outcome in patients with heart failure with preserved ejection fraction (HFpEF). The authors established the association in a subset of the TOPCAT trial (Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist)2 and validated it in external data sets. At a minimum, their observation is new knowledge that may advance our understanding of the pathophysiology of HFpEF. It also indicates that endotrophin-based risk prediction has utility for patients, the health system, and designing future research." @default.
- W4297382026 created "2022-09-28" @default.
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- W4297382026 date "2022-09-27" @default.
- W4297382026 modified "2023-10-16" @default.
- W4297382026 title "Assessing the Utility of Test-Based Prediction Models: Heart Failure as an Example" @default.
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- W4297382026 doi "https://doi.org/10.1056/evide2200229" @default.
- W4297382026 hasPublicationYear "2022" @default.
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