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- W4297457078 endingPage "731" @default.
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- W4297457078 abstract "Over the past years, pituitary hormones and their receptors have been shown to have non-traditional actions that allow them to bypass the hypothalamus-pituitary-effector glands axis. Bone cells-osteoblasts and osteoclasts-express receptors for growth hormone, follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH), adrenocorticotrophic hormone (ACTH), prolactin, oxytocin, and vasopressin. Independent skeletal actions of pituitary hormones on bone have been studied using genetically modified mice with haploinsufficiency and by activating or inactivating the receptors pharmacologically, without altering systemic effector hormone levels. On another front, the discovery of a TSH variant (TSH-βv) in immune cells in the bone marrow and skeletal action of FSHβ through tumor necrosis factor α provides new insights underscoring the integrated physiology of bone-immune-endocrine axis. Here we discuss the interaction of each pituitary hormone with bone and the potential it holds in understanding bone physiology and as a therapeutic target." @default.
- W4297457078 created "2022-09-29" @default.
- W4297457078 creator A5005607794 @default.
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- W4297457078 creator A5029736494 @default.
- W4297457078 creator A5035653029 @default.
- W4297457078 creator A5062649230 @default.
- W4297457078 date "2022-10-31" @default.
- W4297457078 modified "2023-10-18" @default.
- W4297457078 title "Independent Skeletal Actions of Pituitary Hormones" @default.
- W4297457078 cites W1503053258 @default.
- W4297457078 cites W1575065086 @default.
- W4297457078 cites W1594128336 @default.
- W4297457078 cites W1651572921 @default.
- W4297457078 cites W1661646150 @default.
- W4297457078 cites W1712440049 @default.
- W4297457078 cites W1838573250 @default.
- W4297457078 cites W1963748648 @default.
- W4297457078 cites W1966649286 @default.
- W4297457078 cites W1974470716 @default.
- W4297457078 cites W1977409318 @default.
- W4297457078 cites W1978486179 @default.
- W4297457078 cites W1984086676 @default.
- W4297457078 cites W1984797903 @default.
- W4297457078 cites W1986935872 @default.
- W4297457078 cites W1991154677 @default.
- W4297457078 cites W1992692011 @default.
- W4297457078 cites W1995201889 @default.
- W4297457078 cites W1997880790 @default.
- W4297457078 cites W1999187583 @default.
- W4297457078 cites W2002529898 @default.
- W4297457078 cites W2004269531 @default.
- W4297457078 cites W2004626783 @default.
- W4297457078 cites W2008122954 @default.
- W4297457078 cites W2013019376 @default.
- W4297457078 cites W2015337086 @default.
- W4297457078 cites W2016462343 @default.
- W4297457078 cites W2017530514 @default.
- W4297457078 cites W2018585842 @default.
- W4297457078 cites W2019974313 @default.
- W4297457078 cites W2023066512 @default.
- W4297457078 cites W2026517605 @default.
- W4297457078 cites W2026726238 @default.
- W4297457078 cites W2028507841 @default.
- W4297457078 cites W2029992524 @default.
- W4297457078 cites W2031178389 @default.
- W4297457078 cites W2032565269 @default.
- W4297457078 cites W2035181548 @default.
- W4297457078 cites W2038145443 @default.
- W4297457078 cites W2041141700 @default.
- W4297457078 cites W2042534256 @default.
- W4297457078 cites W2043998379 @default.
- W4297457078 cites W2053046452 @default.
- W4297457078 cites W2053358411 @default.
- W4297457078 cites W2054121324 @default.
- W4297457078 cites W2057313543 @default.
- W4297457078 cites W2058688700 @default.
- W4297457078 cites W2059366980 @default.
- W4297457078 cites W2063891211 @default.
- W4297457078 cites W2064543792 @default.
- W4297457078 cites W2067458154 @default.
- W4297457078 cites W2070674566 @default.
- W4297457078 cites W2072102440 @default.
- W4297457078 cites W2073132448 @default.
- W4297457078 cites W2076056181 @default.
- W4297457078 cites W2076480166 @default.
- W4297457078 cites W2077054205 @default.
- W4297457078 cites W2077621719 @default.
- W4297457078 cites W2080802204 @default.
- W4297457078 cites W2081592691 @default.
- W4297457078 cites W2085466965 @default.
- W4297457078 cites W2088025468 @default.
- W4297457078 cites W2089590765 @default.
- W4297457078 cites W2090663991 @default.
- W4297457078 cites W2090741825 @default.
- W4297457078 cites W2093677271 @default.
- W4297457078 cites W2101928531 @default.
- W4297457078 cites W2102437493 @default.
- W4297457078 cites W2103441192 @default.
- W4297457078 cites W2104528426 @default.
- W4297457078 cites W2107941531 @default.
- W4297457078 cites W2108897036 @default.
- W4297457078 cites W2110213602 @default.
- W4297457078 cites W2111894013 @default.
- W4297457078 cites W2115550020 @default.
- W4297457078 cites W2116092458 @default.
- W4297457078 cites W2116800792 @default.
- W4297457078 cites W2122107555 @default.
- W4297457078 cites W2125833975 @default.
- W4297457078 cites W2127573768 @default.
- W4297457078 cites W2129106643 @default.
- W4297457078 cites W2131729118 @default.
- W4297457078 cites W2132333339 @default.
- W4297457078 cites W2145158240 @default.
- W4297457078 cites W2146181521 @default.
- W4297457078 cites W2149936178 @default.
- W4297457078 cites W2154807814 @default.