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• W4297485711 abstract "Study ObjectivesTo develop and implement a multicenter registry aimed to evaluate the clinical impact, safety, and clinical outcomes of focused transesophageal echocardiography (TEE) in the evaluation of critically-ill patients in the emergency department (ED) and intensive care units (ICU).Study Design/MethodsWe designed and implemented a prospective, multicenter, observational study involving adult critically-ill patients in whom focused TEE was performed as part of their routine care for the evaluation of out-of-hospital cardiac arrest (OHCA), in-hospital cardiac arrest (IHCA), initial evaluation of undifferentiated shock, hemodynamic monitoring, and/or procedural guidance in the ED, ICU or operating room (OR) setting (NCT04972526). One academic medical center provided operational and research infrastructure including the RedCap Database and a full-time research manager who coordinated onboarding of participating institutions, including execution of data use agreements and facilitation of data entry. An interdisciplinary scientific oversight committee (SOC) involving physicians with clinical and research experience in the field of TEE, developed and refined the data collection instruments, and convened regularly to assess data completeness and quality. The registry database is composed of five instruments evaluating each specific clinical indication of TEE as a specific cohort of patients. Data elements included patient and procedure characteristics (including findings and procedure-related complications), laboratory values, clinical outcomes, timing of interventions, and TEE video images. Utstein cardiac arrest elements were included in OHCA and IHCA patients as well as resuscitation clinical outcomes. A target of 90% reporting from all eligible cases performed in each participating center was established to minimize selection bias.Results/FindingsDuring the first year of registry implementation, twenty-three hospitals across four countries were onboarded, including 14 EDs, 5 ICUs, and 1 OR. By May 2022 a total of 310 cases have been collected, including 147 (47%) during OHCA, 43 (13%) IHCA, 92 (30%) initial evaluation of shock, 44 (14%) hemodynamic monitoring, and 38 (12%) procedural guidance. Fifteen centers (65%) entered between 1-9 cases, and 8 centers (35%) entered 10 or more cases. Reporting compliance among centers with ≥ 10 cases was 99%.ConclusionA prospective, multicenter, and multidisciplinary registry evaluating the use of focused TEE across acute care settings was successfully implemented. This registry will allow to accelerate the development of outcome-oriented research and knowledge translation on the use of TEE in emergency and critical care settings.Yes, authors have interests to discloseDisclosureFujifilm SonositeConsultant/AdvisorFujifilm SonositeDisclosureCourse Director - The Resuscitative TEE WorkshopOtherCourse Director - The Resuscitative TEE Workshop Study ObjectivesTo develop and implement a multicenter registry aimed to evaluate the clinical impact, safety, and clinical outcomes of focused transesophageal echocardiography (TEE) in the evaluation of critically-ill patients in the emergency department (ED) and intensive care units (ICU). To develop and implement a multicenter registry aimed to evaluate the clinical impact, safety, and clinical outcomes of focused transesophageal echocardiography (TEE) in the evaluation of critically-ill patients in the emergency department (ED) and intensive care units (ICU). Study Design/MethodsWe designed and implemented a prospective, multicenter, observational study involving adult critically-ill patients in whom focused TEE was performed as part of their routine care for the evaluation of out-of-hospital cardiac arrest (OHCA), in-hospital cardiac arrest (IHCA), initial evaluation of undifferentiated shock, hemodynamic monitoring, and/or procedural guidance in the ED, ICU or operating room (OR) setting (NCT04972526). One academic medical center provided operational and research infrastructure including the RedCap Database and a full-time research manager who coordinated onboarding of participating institutions, including execution of data use agreements and facilitation of data entry. An interdisciplinary scientific oversight committee (SOC) involving physicians with clinical and research experience in the field of TEE, developed and refined the data collection instruments, and convened regularly to assess data completeness and quality. The registry database is composed of five instruments evaluating each specific clinical indication of TEE as a specific cohort of patients. Data elements included patient and procedure characteristics (including findings and procedure-related complications), laboratory values, clinical outcomes, timing of interventions, and TEE video images. Utstein cardiac arrest elements were included in OHCA and IHCA patients as well as resuscitation clinical outcomes. A target of 90% reporting from all eligible cases performed in each participating center was established to minimize selection bias. We designed and implemented a prospective, multicenter, observational study involving adult critically-ill patients in whom focused TEE was performed as part of their routine care for the evaluation of out-of-hospital cardiac arrest (OHCA), in-hospital cardiac arrest (IHCA), initial evaluation of undifferentiated shock, hemodynamic monitoring, and/or procedural guidance in the ED, ICU or operating room (OR) setting (NCT04972526). One academic medical center provided operational and research infrastructure including the RedCap Database and a full-time research manager who coordinated onboarding of participating institutions, including execution of data use agreements and facilitation of data entry. An interdisciplinary scientific oversight committee (SOC) involving physicians with clinical and research experience in the field of TEE, developed and refined the data collection instruments, and convened regularly to assess data completeness and quality. The registry database is composed of five instruments evaluating each specific clinical indication of TEE as a specific cohort of patients. Data elements included patient and procedure characteristics (including findings and procedure-related complications), laboratory values, clinical outcomes, timing of interventions, and TEE video images. Utstein cardiac arrest elements were included in OHCA and IHCA patients as well as resuscitation clinical outcomes. A target of 90% reporting from all eligible cases performed in each participating center was established to minimize selection bias. Results/FindingsDuring the first year of registry implementation, twenty-three hospitals across four countries were onboarded, including 14 EDs, 5 ICUs, and 1 OR. By May 2022 a total of 310 cases have been collected, including 147 (47%) during OHCA, 43 (13%) IHCA, 92 (30%) initial evaluation of shock, 44 (14%) hemodynamic monitoring, and 38 (12%) procedural guidance. Fifteen centers (65%) entered between 1-9 cases, and 8 centers (35%) entered 10 or more cases. Reporting compliance among centers with ≥ 10 cases was 99%. During the first year of registry implementation, twenty-three hospitals across four countries were onboarded, including 14 EDs, 5 ICUs, and 1 OR. By May 2022 a total of 310 cases have been collected, including 147 (47%) during OHCA, 43 (13%) IHCA, 92 (30%) initial evaluation of shock, 44 (14%) hemodynamic monitoring, and 38 (12%) procedural guidance. Fifteen centers (65%) entered between 1-9 cases, and 8 centers (35%) entered 10 or more cases. Reporting compliance among centers with ≥ 10 cases was 99%. ConclusionA prospective, multicenter, and multidisciplinary registry evaluating the use of focused TEE across acute care settings was successfully implemented. This registry will allow to accelerate the development of outcome-oriented research and knowledge translation on the use of TEE in emergency and critical care settings.Yes, authors have interests to disclose A prospective, multicenter, and multidisciplinary registry evaluating the use of focused TEE across acute care settings was successfully implemented. This registry will allow to accelerate the development of outcome-oriented research and knowledge translation on the use of TEE in emergency and critical care settings." @default.
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• W4297485711 title "38 Resuscitative TEE Collaborative Registry: Development and Implementation of a Multicenter Registry for Focused Transesophageal Echocardiography (TEE) in the Emergency Department and Intensive Care Settings" @default.
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