Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297497812> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4297497812 endingPage "929" @default.
- W4297497812 startingPage "919" @default.
- W4297497812 abstract "Objective: A new spectrophotometric method for the gliclazide quantitation in dosage forms has been developedMaterial and Method: The subjects of the study were modified-release tablets (Diaglizide 80 mg, Diaglizide MR 60 mg, Diaglizide MR 30 mg, Diabeton MR 60 mg, Gliklada 60 mg). As a reagent, bromocresol green in acetone was used. Analytical equipment: spectrophotometer Specord 200, electronic scales АВТ-120-5DM.Result and Discussion: It has been experimentally determined that gliclazide reacts with bromocresol green in acetone medium at room temperature to form a yellow product with maximum absorption at 411 nm. The method was validated for linearity, accuracy, precision, and robustness. The agent’s optimal concentration was established and the stability of the investigated solutions was checked by measuring their optical density for 30 minutes. Subordination of Beer's law is observed in the range of 62.00 - 94.00 mg/100 ml. The limit of detection is 4.02∙10-6 g/ml, which indicates a high sensitivity of the reaction. The proposed method is validated according to the requirements of the State Pharmacopoeia of Ukraine. The results of the study show that the developed method is simple and affordable to implement and can be used to determine gliclazide in drugs in laboratories for quality control of dosage forms." @default.
- W4297497812 created "2022-09-29" @default.
- W4297497812 creator A5049571407 @default.
- W4297497812 creator A5088917937 @default.
- W4297497812 date "2022-09-28" @default.
- W4297497812 modified "2023-10-18" @default.
- W4297497812 title "TABLETLERDE GLİKLAZİT MİKTAR TAYİNİ İÇİN SPEKTROFOTOMETRİK YÖNTEM GELİŞTİRME VE DOĞRULAMA" @default.
- W4297497812 cites W1972094270 @default.
- W4297497812 cites W2255443375 @default.
- W4297497812 cites W2314402319 @default.
- W4297497812 cites W2532868441 @default.
- W4297497812 cites W2997127882 @default.
- W4297497812 cites W3164601302 @default.
- W4297497812 doi "https://doi.org/10.33483/jfpau.1127275" @default.
- W4297497812 hasPublicationYear "2022" @default.
- W4297497812 type Work @default.
- W4297497812 citedByCount "0" @default.
- W4297497812 crossrefType "journal-article" @default.
- W4297497812 hasAuthorship W4297497812A5049571407 @default.
- W4297497812 hasAuthorship W4297497812A5088917937 @default.
- W4297497812 hasBestOaLocation W42974978121 @default.
- W4297497812 hasConcept C113196181 @default.
- W4297497812 hasConcept C119128265 @default.
- W4297497812 hasConcept C120665830 @default.
- W4297497812 hasConcept C121332964 @default.
- W4297497812 hasConcept C134018914 @default.
- W4297497812 hasConcept C147789679 @default.
- W4297497812 hasConcept C158007255 @default.
- W4297497812 hasConcept C178790620 @default.
- W4297497812 hasConcept C185592680 @default.
- W4297497812 hasConcept C2777448766 @default.
- W4297497812 hasConcept C2779306644 @default.
- W4297497812 hasConcept C2780320262 @default.
- W4297497812 hasConcept C2781213060 @default.
- W4297497812 hasConcept C40875361 @default.
- W4297497812 hasConcept C43617362 @default.
- W4297497812 hasConcept C71924100 @default.
- W4297497812 hasConceptScore W4297497812C113196181 @default.
- W4297497812 hasConceptScore W4297497812C119128265 @default.
- W4297497812 hasConceptScore W4297497812C120665830 @default.
- W4297497812 hasConceptScore W4297497812C121332964 @default.
- W4297497812 hasConceptScore W4297497812C134018914 @default.
- W4297497812 hasConceptScore W4297497812C147789679 @default.
- W4297497812 hasConceptScore W4297497812C158007255 @default.
- W4297497812 hasConceptScore W4297497812C178790620 @default.
- W4297497812 hasConceptScore W4297497812C185592680 @default.
- W4297497812 hasConceptScore W4297497812C2777448766 @default.
- W4297497812 hasConceptScore W4297497812C2779306644 @default.
- W4297497812 hasConceptScore W4297497812C2780320262 @default.
- W4297497812 hasConceptScore W4297497812C2781213060 @default.
- W4297497812 hasConceptScore W4297497812C40875361 @default.
- W4297497812 hasConceptScore W4297497812C43617362 @default.
- W4297497812 hasConceptScore W4297497812C71924100 @default.
- W4297497812 hasLocation W42974978121 @default.
- W4297497812 hasOpenAccess W4297497812 @default.
- W4297497812 hasPrimaryLocation W42974978121 @default.
- W4297497812 hasRelatedWork W1970587968 @default.
- W4297497812 hasRelatedWork W2145535646 @default.
- W4297497812 hasRelatedWork W2949460484 @default.
- W4297497812 hasRelatedWork W2950613640 @default.
- W4297497812 hasRelatedWork W2951174005 @default.
- W4297497812 hasRelatedWork W2951551136 @default.
- W4297497812 hasRelatedWork W2952256733 @default.
- W4297497812 hasRelatedWork W2952556931 @default.
- W4297497812 hasRelatedWork W2952573305 @default.
- W4297497812 hasRelatedWork W2952909973 @default.
- W4297497812 isParatext "false" @default.
- W4297497812 isRetracted "false" @default.
- W4297497812 workType "article" @default.