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- W4297498045 endingPage "130081" @default.
- W4297498045 startingPage "130081" @default.
- W4297498045 abstract "Currently, microplastic pollution is more serious and complicates the toxic effects of other co-existing pollutants in the environment. However, the effect and mechanism of biodegradable plastics on the growth and metabolism of probiotic remain unclear. This work selected Bacillus amyloliquefaciens as model bacterium for a three-day exposure experiment to probe the issues. The results showed that 100 mg/L polylactic acid microplastics (PLA MPs) (3-4 mm, flake shape) caused oxidative damage to cell membranes, disrupted cell wall composition and inhibited cell growth by 21.2-27.5 %. The toxicity was not simply additive or synergistic effects when PLA MPs (100 mg/L) and copper ions (10 mg/L) coexisted. PLA MPs did not significantly increase the toxicity of copper to bacteria, instead triggered some mechanisms to resist the toxicity of copper. The bacteria formed spores to resist PLA MPs, while the copper ions toxicity was weaken by chelation and efflux. It is worth noting that copper ions instead increased the expression of genes related fengycin and iturin then improving the bacteriostatic activity of the probiotic. This paper deeply analyzes the toxicity mechanism of combined pollution on Bacillus amyloliquefacien, and also provides new perspective for helping to inhibit pathogenic bacteria under biodegradable microplastics and metal stress." @default.
- W4297498045 created "2022-09-29" @default.
- W4297498045 creator A5019844372 @default.
- W4297498045 creator A5022569885 @default.
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- W4297498045 creator A5046544355 @default.
- W4297498045 creator A5056348325 @default.
- W4297498045 creator A5065030582 @default.
- W4297498045 creator A5078866844 @default.
- W4297498045 date "2023-02-01" @default.
- W4297498045 modified "2023-10-14" @default.
- W4297498045 title "Investigating the effects of biodegradable microplastics and copper ions on probiotic (Bacillus amyloliquefaciens): Toxicity and application" @default.
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