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- W4297675058 endingPage "327" @default.
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- W4297675058 abstract "Since the turn of the 20th century, since the invention of cardiac electrophysiology, the study of cardiac arrhythmia has proliferated across the globe. Since then, various pharmacological and nonpharmacological methods and treatments have been developed to prevent and abort sudden deaths and other fatal scenarios precipitating cardiac arrhythmia. This chapter begins by looking at the general signs and symptoms that precipitate cardiac arrhythmia. Then it goes into the genetics of various heritable and acquired arrhythmias such as QT-opathies like long-QT syndrome and short-QT syndrome, and other channelopathies. Then the electrophysiology of cardiac impulses and the basic molecular mechanism underlining arrhythmia are discussed. The different types of brady- and tachyarrhythmias have been discussed next. The classic antiarrhythmic drugs and some newer antiarrhythmics have been explained following this, along with their molecular mechanism of action. The chapter ends by discussing the new frontiers into antiarrhythmic drug therapy and some new targets for therapeutics." @default.
- W4297675058 created "2022-09-30" @default.
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- W4297675058 date "2023-01-01" @default.
- W4297675058 modified "2023-10-18" @default.
- W4297675058 title "Mechanism of action of antiarrhythmic drugs" @default.
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