Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297724082> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4297724082 endingPage "145" @default.
- W4297724082 startingPage "132" @default.
- W4297724082 abstract "Eight sessile serrated adenoma (SSA), right colon polypectomies with focal invasive adenocarcinoma or high-grade dysplasia were studied to identify features indicating a high risk of transformation and characterize the morphologic features of serrated dysplasia; 6 cases had invasive adenocarcinoma; 2 were high-grade dysplasia. All 8 were microsatellite unstable-high and had absent hMLH1 nuclear immunoreactivity. The mean patient age at polypectomy was 69.5 years (range, 57.1–83.9 years). Mean polyp maximum dimension was 8.5 mm (range, 6–12 mm). The majority of each polyp was nonmalignant SSA. All 8 cases had an abrupt transition from benign to high-grade in situ or invasive malignancy. In the 6 invasive adenocarcinomas, the neoplasm extended directly down into the submucosa without lateral intramucosal spread. The mean maximum dimension of the invasive adenocarcinoma was 2.9 mm (range, 2–4 mm). All 8 cases had high-grade serrated-type dysplasia. The nonmalignant SSAs had marked expansion of the proliferative zone. Crypts adjacent to malignancy had moderately enlarged nuclei, irregular nuclear membranes, and overly prominent nucleoli. SSA crypts were lined by a variety of gastric-type cells; no cell type predominated. Foci of adjacent crypts had similar cytologic features. Small proximal SSAs can transform into adenocarcinoma without a component of adenomatous dysplasia." @default.
- W4297724082 created "2022-09-30" @default.
- W4297724082 creator A5080604064 @default.
- W4297724082 date "2006-01-01" @default.
- W4297724082 modified "2023-09-30" @default.
- W4297724082 title "Small Colonic Microsatellite Unstable Adenocarcinomas and High-Grade Epithelial Dysplasias in Sessile Serrated Adenoma Polypectomy Specimens" @default.
- W4297724082 doi "https://doi.org/10.1309/v8q9kdd5aj9lnbag" @default.
- W4297724082 hasPublicationYear "2006" @default.
- W4297724082 type Work @default.
- W4297724082 citedByCount "122" @default.
- W4297724082 countsByYear W42977240822012 @default.
- W4297724082 countsByYear W42977240822013 @default.
- W4297724082 countsByYear W42977240822014 @default.
- W4297724082 countsByYear W42977240822015 @default.
- W4297724082 countsByYear W42977240822016 @default.
- W4297724082 countsByYear W42977240822017 @default.
- W4297724082 countsByYear W42977240822018 @default.
- W4297724082 countsByYear W42977240822019 @default.
- W4297724082 countsByYear W42977240822020 @default.
- W4297724082 countsByYear W42977240822021 @default.
- W4297724082 countsByYear W42977240822022 @default.
- W4297724082 countsByYear W42977240822023 @default.
- W4297724082 crossrefType "journal-article" @default.
- W4297724082 hasAuthorship W4297724082A5080604064 @default.
- W4297724082 hasBestOaLocation W42977240821 @default.
- W4297724082 hasConcept C121608353 @default.
- W4297724082 hasConcept C126322002 @default.
- W4297724082 hasConcept C142724271 @default.
- W4297724082 hasConcept C2775894508 @default.
- W4297724082 hasConcept C2776235491 @default.
- W4297724082 hasConcept C2777428134 @default.
- W4297724082 hasConcept C2777936439 @default.
- W4297724082 hasConcept C2778435480 @default.
- W4297724082 hasConcept C2779399171 @default.
- W4297724082 hasConcept C2779534503 @default.
- W4297724082 hasConcept C2780581329 @default.
- W4297724082 hasConcept C2781182431 @default.
- W4297724082 hasConcept C526805850 @default.
- W4297724082 hasConcept C71924100 @default.
- W4297724082 hasConcept C86803240 @default.
- W4297724082 hasConceptScore W4297724082C121608353 @default.
- W4297724082 hasConceptScore W4297724082C126322002 @default.
- W4297724082 hasConceptScore W4297724082C142724271 @default.
- W4297724082 hasConceptScore W4297724082C2775894508 @default.
- W4297724082 hasConceptScore W4297724082C2776235491 @default.
- W4297724082 hasConceptScore W4297724082C2777428134 @default.
- W4297724082 hasConceptScore W4297724082C2777936439 @default.
- W4297724082 hasConceptScore W4297724082C2778435480 @default.
- W4297724082 hasConceptScore W4297724082C2779399171 @default.
- W4297724082 hasConceptScore W4297724082C2779534503 @default.
- W4297724082 hasConceptScore W4297724082C2780581329 @default.
- W4297724082 hasConceptScore W4297724082C2781182431 @default.
- W4297724082 hasConceptScore W4297724082C526805850 @default.
- W4297724082 hasConceptScore W4297724082C71924100 @default.
- W4297724082 hasConceptScore W4297724082C86803240 @default.
- W4297724082 hasIssue "1" @default.
- W4297724082 hasLocation W42977240821 @default.
- W4297724082 hasOpenAccess W4297724082 @default.
- W4297724082 hasPrimaryLocation W42977240821 @default.
- W4297724082 hasRelatedWork W1578924265 @default.
- W4297724082 hasRelatedWork W164697185 @default.
- W4297724082 hasRelatedWork W1929238403 @default.
- W4297724082 hasRelatedWork W1998311894 @default.
- W4297724082 hasRelatedWork W2005504289 @default.
- W4297724082 hasRelatedWork W2013763071 @default.
- W4297724082 hasRelatedWork W2026267347 @default.
- W4297724082 hasRelatedWork W2409051667 @default.
- W4297724082 hasRelatedWork W2523886685 @default.
- W4297724082 hasRelatedWork W4312316148 @default.
- W4297724082 hasVolume "125" @default.
- W4297724082 isParatext "false" @default.
- W4297724082 isRetracted "false" @default.
- W4297724082 workType "article" @default.