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- W4297759969 abstract "We report a case of 12-year-old boy diagnosed with an unclassified sex cord stromal testicular tumor after a mild testicular trauma and the unclear ultrasound finding of a testicular mass. Physical examination was significant for a mass in the right testis. Scrotal magnetic resonance revealed an 8 millimeters nodular lesion suggestive of a Leydig cell tumor. Tumor markers were negative. The patient underwent a right radical orchiectomy plus implantation of a testicular prosthesis. Tumor cells expressed inhibin, WT 1, CD 56, CD99, vimentin and actin. Pathological diagnosis was unclassified sex cord stromal tumor confined to the testis. Metastatic workup by CT was negative. Unclassified sex cord-stromal tumors are infrequent and show an indeterminate differentiation of tumor cells that cannot be characterized with light microscopy towards Leydig, Sertoli, granulosa or theca cells. Immunohistochemistry helps in the differential diagnosis.Due to the risk of malignancy, local recurrence and uncertain biological behavior, radical orchiectomy is recommended, and a metastatic workup should be performed. Keywords: children; orchiectomy; sex cord-stromal tumor; scrotal ultrasound; testicular tumor" @default.
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- W4297759969 date "2022-03-16" @default.
- W4297759969 modified "2023-10-01" @default.
- W4297759969 title "Unclassified testicular sex cord-stromal tumors in children" @default.
- W4297759969 doi "https://doi.org/10.52768/2766-7820/1740" @default.
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