FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297810568> ?p ?o ?g. }

• W4297810568 endingPage "5419" @default.
• W4297810568 startingPage "5411" @default.
• W4297810568 abstract "Organelle transport is vital for the development and maintenance of axons, in which the distances between sites of organelle biogenesis, function, and recycling or degradation can be vast. Movement of mitochondria in axons can serve as a general model for how all organelles move: mitochondria are easy to identify, they move along both microtubule and actin tracks, they pause and change direction, and their transport is modulated in response to physiological signals. However, they can be distinguished from other axonal organelles by the complexity of their movement and their unique functions in aerobic metabolism, calcium homeostasis and cell death. Mitochondria are thus of special interest in relating defects in axonal transport to neuropathies and degenerative diseases of the nervous system. Studies of mitochondrial transport in axons are beginning to illuminate fundamental aspects of the distribution mechanism. They use motors of one or more kinesin families, along with cytoplasmic dynein, to translocate along microtubules, and bidirectional movement may be coordinated through interaction between dynein and kinesin-1. Translocation along actin filaments is probably driven by myosin V, but the protein(s) that mediate docking with actin filaments remain unknown. Signaling through the PI 3-kinase pathway has been implicated in regulation of mitochondrial movement and docking in the axon, and additional mitochondrial linker and regulatory proteins, such as Milton and Miro, have recently been described." @default.
• W4297810568 created "2022-10-01" @default.
• W4297810568 creator A5036737802 @default.
• W4297810568 creator A5051589477 @default.
• W4297810568 date "2005-12-01" @default.
• W4297810568 modified "2023-10-16" @default.
• W4297810568 title "The axonal transport of mitochondria" @default.
• W4297810568 cites W1516420510 @default.
• W4297810568 cites W1532443308 @default.
• W4297810568 cites W1554595041 @default.
• W4297810568 cites W1567321500 @default.
• W4297810568 cites W1577751913 @default.
• W4297810568 cites W1643772655 @default.
• W4297810568 cites W1877780738 @default.
• W4297810568 cites W1906431592 @default.
• W4297810568 cites W1934663712 @default.
• W4297810568 cites W1962426462 @default.
• W4297810568 cites W1964565356 @default.
• W4297810568 cites W1964791077 @default.
• W4297810568 cites W1967497524 @default.
• W4297810568 cites W1970182993 @default.
• W4297810568 cites W1970356391 @default.
• W4297810568 cites W1970579968 @default.
• W4297810568 cites W1971831293 @default.
• W4297810568 cites W1972478580 @default.
• W4297810568 cites W1974750801 @default.
• W4297810568 cites W1975428625 @default.
• W4297810568 cites W1978436090 @default.
• W4297810568 cites W1980917973 @default.
• W4297810568 cites W1981095308 @default.
• W4297810568 cites W1981705617 @default.
• W4297810568 cites W1983587568 @default.
• W4297810568 cites W1984168802 @default.
• W4297810568 cites W1985693768 @default.
• W4297810568 cites W1989133066 @default.
• W4297810568 cites W1992307393 @default.
• W4297810568 cites W1992709431 @default.
• W4297810568 cites W1993621881 @default.
• W4297810568 cites W1995114050 @default.
• W4297810568 cites W1996061686 @default.
• W4297810568 cites W1997216533 @default.
• W4297810568 cites W1998263574 @default.
• W4297810568 cites W2002849044 @default.
• W4297810568 cites W2005614635 @default.
• W4297810568 cites W2006011383 @default.
• W4297810568 cites W2008263077 @default.
• W4297810568 cites W2012855723 @default.
• W4297810568 cites W2019979996 @default.
• W4297810568 cites W2025164890 @default.
• W4297810568 cites W2028177630 @default.
• W4297810568 cites W2029120000 @default.
• W4297810568 cites W2029296655 @default.
• W4297810568 cites W2029720946 @default.
• W4297810568 cites W2030113770 @default.
• W4297810568 cites W2034614968 @default.
• W4297810568 cites W2034725792 @default.
• W4297810568 cites W2035318827 @default.
• W4297810568 cites W2036791184 @default.
• W4297810568 cites W2038759241 @default.
• W4297810568 cites W2040503127 @default.
• W4297810568 cites W2041944933 @default.
• W4297810568 cites W2042011713 @default.
• W4297810568 cites W2042756883 @default.
• W4297810568 cites W2042829586 @default.
• W4297810568 cites W2044031210 @default.
• W4297810568 cites W2045912466 @default.
• W4297810568 cites W2048250361 @default.
• W4297810568 cites W2049159412 @default.
• W4297810568 cites W2054472159 @default.
• W4297810568 cites W2055022577 @default.
• W4297810568 cites W2056409809 @default.
• W4297810568 cites W2056607792 @default.
• W4297810568 cites W2057963096 @default.
• W4297810568 cites W2058995799 @default.
• W4297810568 cites W2062535587 @default.
• W4297810568 cites W2062742732 @default.
• W4297810568 cites W2062780012 @default.
• W4297810568 cites W2064170659 @default.
• W4297810568 cites W2064497291 @default.
• W4297810568 cites W2065035577 @default.
• W4297810568 cites W2065384834 @default.
• W4297810568 cites W2066575706 @default.
• W4297810568 cites W2066874327 @default.
• W4297810568 cites W2066978741 @default.
• W4297810568 cites W2067432764 @default.
• W4297810568 cites W2068044068 @default.
• W4297810568 cites W2068277146 @default.
• W4297810568 cites W2070262845 @default.
• W4297810568 cites W2071854131 @default.
• W4297810568 cites W2072154749 @default.
• W4297810568 cites W2072596507 @default.
• W4297810568 cites W2073353027 @default.
• W4297810568 cites W2074359789 @default.
• W4297810568 cites W2075095119 @default.
• W4297810568 cites W2075227275 @default.
• W4297810568 cites W2077977333 @default.
• W4297810568 cites W2078023075 @default.
• W4297810568 cites W2078909919 @default.

• next