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W4297818389 abstract "The MEDIOLA (NCT02734004) study evaluated the efficacy and safety of olaparib+durvalumab (O+D doublet cohort) and O+D+bevacizumab (O+D+B triplet cohort) in patients (pts) with non-germline BRCA-mutated (non-gBRCAm) platinum-sensitive relapsed ovarian cancer (PSR OC). Previous efficacy data showed median progression-free survival (PFS) (95% CI) of 5.5 (3.6–7.5) and 14.7 (10.0–18.1) months (mo) with O+D and O+D+B, respectively (Drew et al, ESMO 2020). We now present the final analysis of overall survival (OS) and disease control rate (DCR) at 56 weeks (wks) in the O+D and O+D+B cohorts." @default.
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W4297818389 date "2022-09-01" @default.
W4297818389 modified "2023-10-14" @default.
W4297818389 title "529MO Phase II study of olaparib plus durvalumab with or without bevacizumab (MEDIOLA): Final analysis of overall survival in patients with non-germline BRCA-mutated platinum-sensitive relapsed ovarian cancer" @default.
W4297818389 doi "https://doi.org/10.1016/j.annonc.2022.07.657" @default.
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