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• W4297841273 startingPage "51" @default.
• W4297841273 abstract "Inflammation is crucial to maintain homeostasis in the body. The contribution of fatty acids to the inflammatory process is exerted through a variety of mechanisms leading to cell surface modifications, activation of intracellular receptors that control inflammatory signaling processes, and changes in gene expression patterns. While long-chain saturated fatty acids induce NFkB pathway activation through TLR-4 binding, unsaturated fatty acids, such as monounsaturated, polyunsaturated, and conjugated fatty acids’ antiinflammatory ability is mediated through PPARs or GPR120. Moreover, these unsaturated fatty acids, especially omega-3 fatty acids, have immunomodulatory and cytoprotective potential, which is highly relevant for diseases with a neuroinflammatory component, such as obesity, Alzheimer’s disease, multiple sclerosis, and schizophrenia." @default.
• W4297841273 created "2022-10-01" @default.
• W4297841273 creator A5065157625 @default.
• W4297841273 creator A5071169141 @default.
• W4297841273 creator A5075154167 @default.
• W4297841273 creator A5078617585 @default.
• W4297841273 date "2023-01-01" @default.
• W4297841273 modified "2023-10-13" @default.
• W4297841273 title "The pro- and antiinflammatory activity of fatty acids" @default.
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