Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297963208> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W4297963208 endingPage "768" @default.
- W4297963208 startingPage "767" @default.
- W4297963208 abstract "The clotting of blood in vitro involves the activation of clotting factors and platelets. Retraction of the clot then takes place followed by breakdown of the clot by fibrinolysis. All of these steps can be followed by studying the tensile strength of the clot by thromboelastography (TEG) and rotational thromboelastometry (ROTEM), both methods identified under the umbrella term “viscoelastography.” This methodology was first described by Helmut Hartert as “thrombus stressography” in 1948.[1] Further technologic advance has led to the development of several new devices. TEG and ROTEM represent the two most commonly used methods. In the former, a sample of citrated blood is placed in an oscillating cup containing kaolin. Calcium is added to start the clotting process. A plot of the reaction is shown in [Fig. 1]. The initial reaction time is designated as R-time with normal values ranging from 4 to 8 minutes. This measures the function of clotting factors and is thus affected by anticoagulants. The time to reach a clot strength of 20 mm is the K-time and ranges from 1 to 3 minutes. The α-angle, ranging from 55 to 78 degrees, is the slope of the tracing that represents the rate of clot formation. The maximal amplitude (MA) of the tracing represents the greatest clot strength ranging from 50 to 60 mm. As fibrinolysis takes place, the MA decreases. The percentage of the MA at 30 minutes is the lysis index and ranges from 0 to 15%. The first part of the tracing (R-time, K-time, α-angle, and MA) is a function of the quantity and quality of the clotting factors and of platelets, and the second part those of fibrinolysis. In the rapid version of TEG, clotting is further accelerated by addition of tissue factor. In thromboelastometry, also known as ROTEM, the cup containing the test sample is stationary while the torque of the clot is picked up by a rotating pin." @default.
- W4297963208 created "2022-10-01" @default.
- W4297963208 creator A5015421254 @default.
- W4297963208 creator A5041923386 @default.
- W4297963208 creator A5047995082 @default.
- W4297963208 creator A5063490330 @default.
- W4297963208 date "2022-09-29" @default.
- W4297963208 modified "2023-09-26" @default.
- W4297963208 title "Emerging Use of Viscoelastography in Thrombosis and Hemostasis: A Challenge to Conventional Coagulation Tests? Part I: The Use of Thromboelastography and Thromboelastometry in the Assessment of Hemostatic Function" @default.
- W4297963208 cites W3010738012 @default.
- W4297963208 cites W4294543991 @default.
- W4297963208 cites W4295762071 @default.
- W4297963208 cites W4296027399 @default.
- W4297963208 cites W4296163438 @default.
- W4297963208 cites W4297963202 @default.
- W4297963208 cites W4297963215 @default.
- W4297963208 cites W4297963278 @default.
- W4297963208 cites W4297963310 @default.
- W4297963208 cites W4297963393 @default.
- W4297963208 doi "https://doi.org/10.1055/s-0042-1756700" @default.
- W4297963208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36174599" @default.
- W4297963208 hasPublicationYear "2022" @default.
- W4297963208 type Work @default.
- W4297963208 citedByCount "1" @default.
- W4297963208 countsByYear W42979632082023 @default.
- W4297963208 crossrefType "journal-article" @default.
- W4297963208 hasAuthorship W4297963208A5015421254 @default.
- W4297963208 hasAuthorship W4297963208A5041923386 @default.
- W4297963208 hasAuthorship W4297963208A5047995082 @default.
- W4297963208 hasAuthorship W4297963208A5063490330 @default.
- W4297963208 hasBestOaLocation W42979632081 @default.
- W4297963208 hasConcept C126322002 @default.
- W4297963208 hasConcept C136229726 @default.
- W4297963208 hasConcept C141071460 @default.
- W4297963208 hasConcept C203014093 @default.
- W4297963208 hasConcept C26809991 @default.
- W4297963208 hasConcept C2776825266 @default.
- W4297963208 hasConcept C2777664302 @default.
- W4297963208 hasConcept C2778382381 @default.
- W4297963208 hasConcept C2778589496 @default.
- W4297963208 hasConcept C2780868729 @default.
- W4297963208 hasConcept C2781362458 @default.
- W4297963208 hasConcept C2910686401 @default.
- W4297963208 hasConcept C42219234 @default.
- W4297963208 hasConcept C54173615 @default.
- W4297963208 hasConcept C71924100 @default.
- W4297963208 hasConcept C77171857 @default.
- W4297963208 hasConceptScore W4297963208C126322002 @default.
- W4297963208 hasConceptScore W4297963208C136229726 @default.
- W4297963208 hasConceptScore W4297963208C141071460 @default.
- W4297963208 hasConceptScore W4297963208C203014093 @default.
- W4297963208 hasConceptScore W4297963208C26809991 @default.
- W4297963208 hasConceptScore W4297963208C2776825266 @default.
- W4297963208 hasConceptScore W4297963208C2777664302 @default.
- W4297963208 hasConceptScore W4297963208C2778382381 @default.
- W4297963208 hasConceptScore W4297963208C2778589496 @default.
- W4297963208 hasConceptScore W4297963208C2780868729 @default.
- W4297963208 hasConceptScore W4297963208C2781362458 @default.
- W4297963208 hasConceptScore W4297963208C2910686401 @default.
- W4297963208 hasConceptScore W4297963208C42219234 @default.
- W4297963208 hasConceptScore W4297963208C54173615 @default.
- W4297963208 hasConceptScore W4297963208C71924100 @default.
- W4297963208 hasConceptScore W4297963208C77171857 @default.
- W4297963208 hasIssue "07" @default.
- W4297963208 hasLocation W42979632081 @default.
- W4297963208 hasLocation W42979632082 @default.
- W4297963208 hasOpenAccess W4297963208 @default.
- W4297963208 hasPrimaryLocation W42979632081 @default.
- W4297963208 hasRelatedWork W1499447375 @default.
- W4297963208 hasRelatedWork W1992416676 @default.
- W4297963208 hasRelatedWork W1993751516 @default.
- W4297963208 hasRelatedWork W2018041233 @default.
- W4297963208 hasRelatedWork W2142809579 @default.
- W4297963208 hasRelatedWork W2323197488 @default.
- W4297963208 hasRelatedWork W2419693331 @default.
- W4297963208 hasRelatedWork W2466052074 @default.
- W4297963208 hasRelatedWork W2510800681 @default.
- W4297963208 hasRelatedWork W2184873053 @default.
- W4297963208 hasVolume "48" @default.
- W4297963208 isParatext "false" @default.
- W4297963208 isRetracted "false" @default.
- W4297963208 workType "article" @default.