Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297982783> ?p ?o ?g. }
- W4297982783 endingPage "13950" @default.
- W4297982783 startingPage "13944" @default.
- W4297982783 abstract "Disorder of lipid homeostasis is closely associated with a variety of diseases. Although mass spectrometry (MS) approaches have been well developed for the characterization of lipids, it still lacks an integrated and compact MS system that is capable of rapid and detailed lipid structural characterization and can be conveniently transferred into different laboratories. In this work, we describe a novel miniature MS system with the capability of both ozone-induced dissociation (OzID) and collision-induced dissociation (CID) for the assignment of sites of unsaturation and sn-positions in glycerolipids. A miniature ozone generator was developed, which can be operated at a relatively high pressure. By maintaining high-concentration ozone inside the linear ion trap, OzID efficiency was significantly improved for the identification of C═C locations in unsaturated lipids, with reaction times as short as 10 ms. Finally, the miniature OzID MS system was applied to the analysis of C═C locations and sn-positions of lipids from biological samples. Direct sampling and fast detection of changes in phospholipid isomers were demonstrated for the rapid discrimination of breast cancer tissue samples, showing the potential of the miniature OzID MS system for point-of-care analysis of lipid isomer biomarkers in complex samples." @default.
- W4297982783 created "2022-10-01" @default.
- W4297982783 creator A5009310130 @default.
- W4297982783 creator A5012412448 @default.
- W4297982783 creator A5041181642 @default.
- W4297982783 creator A5062534695 @default.
- W4297982783 creator A5063584345 @default.
- W4297982783 creator A5063879522 @default.
- W4297982783 creator A5079252934 @default.
- W4297982783 creator A5090731919 @default.
- W4297982783 date "2022-09-29" @default.
- W4297982783 modified "2023-10-17" @default.
- W4297982783 title "Development of a Miniature Mass Spectrometry System for Point-of-Care Analysis of Lipid Isomers Based on Ozone-Induced Dissociation" @default.
- W4297982783 cites W1964992571 @default.
- W4297982783 cites W1968072363 @default.
- W4297982783 cites W1974356017 @default.
- W4297982783 cites W1986698362 @default.
- W4297982783 cites W1992690229 @default.
- W4297982783 cites W2011616239 @default.
- W4297982783 cites W2037249351 @default.
- W4297982783 cites W2043453309 @default.
- W4297982783 cites W2058462430 @default.
- W4297982783 cites W2059544508 @default.
- W4297982783 cites W2078394205 @default.
- W4297982783 cites W2086102771 @default.
- W4297982783 cites W2115944543 @default.
- W4297982783 cites W2147753992 @default.
- W4297982783 cites W2161210686 @default.
- W4297982783 cites W219788724 @default.
- W4297982783 cites W2412521776 @default.
- W4297982783 cites W2486975460 @default.
- W4297982783 cites W2512745407 @default.
- W4297982783 cites W2566405543 @default.
- W4297982783 cites W2591007340 @default.
- W4297982783 cites W2593659162 @default.
- W4297982783 cites W2610038447 @default.
- W4297982783 cites W2742124344 @default.
- W4297982783 cites W2753124759 @default.
- W4297982783 cites W2761019098 @default.
- W4297982783 cites W2773750852 @default.
- W4297982783 cites W2802905882 @default.
- W4297982783 cites W2804741598 @default.
- W4297982783 cites W2885062223 @default.
- W4297982783 cites W2886240473 @default.
- W4297982783 cites W2900512347 @default.
- W4297982783 cites W2905570673 @default.
- W4297982783 cites W2907911959 @default.
- W4297982783 cites W2908070307 @default.
- W4297982783 cites W2908586978 @default.
- W4297982783 cites W2913095286 @default.
- W4297982783 cites W2968180542 @default.
- W4297982783 cites W2978688426 @default.
- W4297982783 cites W2981542397 @default.
- W4297982783 cites W3014022783 @default.
- W4297982783 cites W3080082387 @default.
- W4297982783 cites W3127764969 @default.
- W4297982783 cites W3134406871 @default.
- W4297982783 cites W4223950975 @default.
- W4297982783 cites W4225131254 @default.
- W4297982783 doi "https://doi.org/10.1021/acs.analchem.2c03112" @default.
- W4297982783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36176011" @default.
- W4297982783 hasPublicationYear "2022" @default.
- W4297982783 type Work @default.
- W4297982783 citedByCount "4" @default.
- W4297982783 countsByYear W42979827832023 @default.
- W4297982783 crossrefType "journal-article" @default.
- W4297982783 hasAuthorship W4297982783A5009310130 @default.
- W4297982783 hasAuthorship W4297982783A5012412448 @default.
- W4297982783 hasAuthorship W4297982783A5041181642 @default.
- W4297982783 hasAuthorship W4297982783A5062534695 @default.
- W4297982783 hasAuthorship W4297982783A5063584345 @default.
- W4297982783 hasAuthorship W4297982783A5063879522 @default.
- W4297982783 hasAuthorship W4297982783A5079252934 @default.
- W4297982783 hasAuthorship W4297982783A5090731919 @default.
- W4297982783 hasConcept C102931765 @default.
- W4297982783 hasConcept C113196181 @default.
- W4297982783 hasConcept C162356407 @default.
- W4297982783 hasConcept C176107965 @default.
- W4297982783 hasConcept C178790620 @default.
- W4297982783 hasConcept C185592680 @default.
- W4297982783 hasConcept C201268389 @default.
- W4297982783 hasConcept C2778918659 @default.
- W4297982783 hasConcept C31827203 @default.
- W4297982783 hasConcept C41625074 @default.
- W4297982783 hasConcept C43617362 @default.
- W4297982783 hasConcept C508106653 @default.
- W4297982783 hasConcept C55493867 @default.
- W4297982783 hasConceptScore W4297982783C102931765 @default.
- W4297982783 hasConceptScore W4297982783C113196181 @default.
- W4297982783 hasConceptScore W4297982783C162356407 @default.
- W4297982783 hasConceptScore W4297982783C176107965 @default.
- W4297982783 hasConceptScore W4297982783C178790620 @default.
- W4297982783 hasConceptScore W4297982783C185592680 @default.
- W4297982783 hasConceptScore W4297982783C201268389 @default.
- W4297982783 hasConceptScore W4297982783C2778918659 @default.
- W4297982783 hasConceptScore W4297982783C31827203 @default.
- W4297982783 hasConceptScore W4297982783C41625074 @default.
- W4297982783 hasConceptScore W4297982783C43617362 @default.