FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297990400> ?p ?o ?g. }

• W4297990400 endingPage "13851" @default.
• W4297990400 startingPage "13842" @default.
• W4297990400 abstract "The nucleolus, as a main cellular stress receptor, is the hub of the stress response driving cancer development and has great research value in the field of organelle-targeting photothermal therapy. However, there are few studies focused on monitoring nucleolar stress response and revealing how the energy metabolism of cells regulates the nucleolar stress response during photothermal therapy. Herein, by designing a nucleolus-targeting and ATP- and photothermal-responsive plasmonic fluorescent nanoprobe (AuNRs-CDs) based on gold nanorods (AuNRs) and fluorescent carbon quantum dots (CDs), we achieved real-time fluorescence imaging of nucleus morphology while monitoring changes of ATP content at the subcellular level. We found that the green fluorescence diminished at 5 min of photothermal therapy, and the nucleolus morphology began to shrink and became smaller in cancerous HepG2 cells. In contrast, there is no significant change of green fluorescence in the nucleolar region of normal HL-7702 cells. ATP content monitoring also showed similar results. Apparently, in response to photothermal stimuli, cancerous cells produce more ATP (energy) along with obvious change in nucleolus morphology and state compared to normal cells under the hyperthermia-induced cell apoptosis. The developed AuNRs-CDs as a nucleolus imaging nanoprobe and effective photothermal agent present promising applications for nucleolar stress studies and targeted photothermal therapy." @default.
• W4297990400 created "2022-10-01" @default.
• W4297990400 creator A5036477294 @default.
• W4297990400 creator A5043920069 @default.
• W4297990400 creator A5056168495 @default.
• W4297990400 creator A5070950656 @default.
• W4297990400 creator A5076327240 @default.
• W4297990400 creator A5088230867 @default.
• W4297990400 date "2022-09-29" @default.
• W4297990400 modified "2023-09-30" @default.
• W4297990400 title "Monitoring Stress Response Difference in Nucleolus Morphology and ATP Content Changes during Hyperthermia Cell Apoptosis with Plasmonic Fluorescent Nanoprobes" @default.
• W4297990400 cites W1572157649 @default.
• W4297990400 cites W2022594178 @default.
• W4297990400 cites W2058201913 @default.
• W4297990400 cites W2062993008 @default.
• W4297990400 cites W2071007484 @default.
• W4297990400 cites W2092340487 @default.
• W4297990400 cites W2095009792 @default.
• W4297990400 cites W2129104457 @default.
• W4297990400 cites W2171804757 @default.
• W4297990400 cites W2291888828 @default.
• W4297990400 cites W2564019181 @default.
• W4297990400 cites W2613244157 @default.
• W4297990400 cites W2745734064 @default.
• W4297990400 cites W2792453304 @default.
• W4297990400 cites W2890967653 @default.
• W4297990400 cites W2895767281 @default.
• W4297990400 cites W2941648040 @default.
• W4297990400 cites W2948616030 @default.
• W4297990400 cites W2954890789 @default.
• W4297990400 cites W2956474901 @default.
• W4297990400 cites W2963664906 @default.
• W4297990400 cites W2972619137 @default.
• W4297990400 cites W2998614401 @default.
• W4297990400 cites W3004483809 @default.
• W4297990400 cites W3010270272 @default.
• W4297990400 cites W3096787175 @default.
• W4297990400 cites W3105951105 @default.
• W4297990400 cites W3125532084 @default.
• W4297990400 cites W3128438146 @default.
• W4297990400 cites W3155145149 @default.
• W4297990400 cites W3175767205 @default.
• W4297990400 cites W3176827396 @default.
• W4297990400 cites W3185339946 @default.
• W4297990400 cites W3188451570 @default.
• W4297990400 cites W3205643062 @default.
• W4297990400 cites W3209991777 @default.
• W4297990400 cites W4223600679 @default.
• W4297990400 doi "https://doi.org/10.1021/acs.analchem.2c02464" @default.
• W4297990400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36174112" @default.
• W4297990400 hasPublicationYear "2022" @default.
• W4297990400 type Work @default.
• W4297990400 citedByCount "1" @default.
• W4297990400 countsByYear W42979904002023 @default.
• W4297990400 crossrefType "journal-article" @default.
• W4297990400 hasAuthorship W4297990400A5036477294 @default.
• W4297990400 hasAuthorship W4297990400A5043920069 @default.
• W4297990400 hasAuthorship W4297990400A5056168495 @default.
• W4297990400 hasAuthorship W4297990400A5070950656 @default.
• W4297990400 hasAuthorship W4297990400A5076327240 @default.
• W4297990400 hasAuthorship W4297990400A5088230867 @default.
• W4297990400 hasConcept C120665830 @default.
• W4297990400 hasConcept C121332964 @default.
• W4297990400 hasConcept C121608353 @default.
• W4297990400 hasConcept C12554922 @default.
• W4297990400 hasConcept C151730666 @default.
• W4297990400 hasConcept C155672457 @default.
• W4297990400 hasConcept C16387964 @default.
• W4297990400 hasConcept C169274487 @default.
• W4297990400 hasConcept C171250308 @default.
• W4297990400 hasConcept C182606246 @default.
• W4297990400 hasConcept C183873130 @default.
• W4297990400 hasConcept C185592680 @default.
• W4297990400 hasConcept C190062978 @default.
• W4297990400 hasConcept C190283241 @default.
• W4297990400 hasConcept C192562407 @default.
• W4297990400 hasConcept C2777742735 @default.
• W4297990400 hasConcept C2779949491 @default.
• W4297990400 hasConcept C54355233 @default.
• W4297990400 hasConcept C55493867 @default.
• W4297990400 hasConcept C86803240 @default.
• W4297990400 hasConcept C91881484 @default.
• W4297990400 hasConcept C95444343 @default.
• W4297990400 hasConcept C96232424 @default.
• W4297990400 hasConceptScore W4297990400C120665830 @default.
• W4297990400 hasConceptScore W4297990400C121332964 @default.
• W4297990400 hasConceptScore W4297990400C121608353 @default.
• W4297990400 hasConceptScore W4297990400C12554922 @default.
• W4297990400 hasConceptScore W4297990400C151730666 @default.
• W4297990400 hasConceptScore W4297990400C155672457 @default.
• W4297990400 hasConceptScore W4297990400C16387964 @default.
• W4297990400 hasConceptScore W4297990400C169274487 @default.
• W4297990400 hasConceptScore W4297990400C171250308 @default.
• W4297990400 hasConceptScore W4297990400C182606246 @default.
• W4297990400 hasConceptScore W4297990400C183873130 @default.
• W4297990400 hasConceptScore W4297990400C185592680 @default.
• W4297990400 hasConceptScore W4297990400C190062978 @default.
• W4297990400 hasConceptScore W4297990400C190283241 @default.

• next