Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297997773> ?p ?o ?g. }
- W4297997773 abstract "Natural products have been extensively applied in clinical practice, characterized by multi-component and multi-target, many pharmacodynamic substances, complex action mechanisms, and various physiological activities. For the oral administration of natural products, the gut microbiota and clinical efficacy are closely related, but this relationship remains unclear. Gut microbes play an important role in the transformation and utilization of natural products caused by the diversity of enzyme systems. Effective components such as flavonoids, alkaloids, lignans, and phenols cannot be metabolized directly through human digestive enzymes but can be transformed by enzymes produced by gut microorganisms and then utilized. Therefore, the focus is paid to the metabolism of natural products through the gut microbiota. In the present study, we systematically reviewed the studies about gut microbiota and their effect on the biotransformation of various components of natural products and highlighted the involved common bacteria, reaction types, pharmacological actions, and research methods. This study aims to provide theoretical support for the clinical application in the prevention and treatment of diseases and provide new ideas for studying natural products based on gut biotransformation." @default.
- W4297997773 created "2022-10-01" @default.
- W4297997773 creator A5029363724 @default.
- W4297997773 creator A5031973958 @default.
- W4297997773 creator A5038884599 @default.
- W4297997773 creator A5052911872 @default.
- W4297997773 creator A5072789121 @default.
- W4297997773 creator A5077279687 @default.
- W4297997773 date "2022-09-29" @default.
- W4297997773 modified "2023-10-14" @default.
- W4297997773 title "Potential roles of gut microbes in biotransformation of natural products: An overview" @default.
- W4297997773 cites W1171238582 @default.
- W4297997773 cites W1496642049 @default.
- W4297997773 cites W1766127974 @default.
- W4297997773 cites W1808270170 @default.
- W4297997773 cites W184596582 @default.
- W4297997773 cites W1895341072 @default.
- W4297997773 cites W1902519942 @default.
- W4297997773 cites W1919807845 @default.
- W4297997773 cites W1970577628 @default.
- W4297997773 cites W1970878570 @default.
- W4297997773 cites W1974041751 @default.
- W4297997773 cites W1974846806 @default.
- W4297997773 cites W1980253429 @default.
- W4297997773 cites W1982522900 @default.
- W4297997773 cites W1983200183 @default.
- W4297997773 cites W1984872960 @default.
- W4297997773 cites W1985588407 @default.
- W4297997773 cites W1986340031 @default.
- W4297997773 cites W1986699402 @default.
- W4297997773 cites W1988330677 @default.
- W4297997773 cites W1995216632 @default.
- W4297997773 cites W1996929337 @default.
- W4297997773 cites W1997267357 @default.
- W4297997773 cites W1998178455 @default.
- W4297997773 cites W2002766413 @default.
- W4297997773 cites W2005555474 @default.
- W4297997773 cites W2007298512 @default.
- W4297997773 cites W2007768116 @default.
- W4297997773 cites W2013107815 @default.
- W4297997773 cites W2014844547 @default.
- W4297997773 cites W2018438226 @default.
- W4297997773 cites W2019088705 @default.
- W4297997773 cites W2021641458 @default.
- W4297997773 cites W2022637215 @default.
- W4297997773 cites W2024026026 @default.
- W4297997773 cites W2025041366 @default.
- W4297997773 cites W2029625739 @default.
- W4297997773 cites W2030630440 @default.
- W4297997773 cites W2038199402 @default.
- W4297997773 cites W2039698474 @default.
- W4297997773 cites W2042293357 @default.
- W4297997773 cites W2047888249 @default.
- W4297997773 cites W2048152594 @default.
- W4297997773 cites W2048668794 @default.
- W4297997773 cites W2049146274 @default.
- W4297997773 cites W2051595513 @default.
- W4297997773 cites W2053265328 @default.
- W4297997773 cites W2053680606 @default.
- W4297997773 cites W2053725987 @default.
- W4297997773 cites W2055363500 @default.
- W4297997773 cites W2057474001 @default.
- W4297997773 cites W2059272234 @default.
- W4297997773 cites W2060685756 @default.
- W4297997773 cites W2060997715 @default.
- W4297997773 cites W2061593614 @default.
- W4297997773 cites W2065618553 @default.
- W4297997773 cites W2069391842 @default.
- W4297997773 cites W2073345735 @default.
- W4297997773 cites W2073677430 @default.
- W4297997773 cites W2075165930 @default.
- W4297997773 cites W2078470138 @default.
- W4297997773 cites W2080561646 @default.
- W4297997773 cites W2082600894 @default.
- W4297997773 cites W2083120074 @default.
- W4297997773 cites W2095213598 @default.
- W4297997773 cites W2097066394 @default.
- W4297997773 cites W2098910106 @default.
- W4297997773 cites W2099141426 @default.
- W4297997773 cites W2104637389 @default.
- W4297997773 cites W2107495325 @default.
- W4297997773 cites W2108281900 @default.
- W4297997773 cites W2110491379 @default.
- W4297997773 cites W2111822142 @default.
- W4297997773 cites W2114089110 @default.
- W4297997773 cites W2115188038 @default.
- W4297997773 cites W2116379567 @default.
- W4297997773 cites W2125330288 @default.
- W4297997773 cites W2129256872 @default.
- W4297997773 cites W2132176892 @default.
- W4297997773 cites W2132645356 @default.
- W4297997773 cites W2138584508 @default.
- W4297997773 cites W2144177252 @default.
- W4297997773 cites W2148103005 @default.
- W4297997773 cites W2149515881 @default.
- W4297997773 cites W2154723930 @default.
- W4297997773 cites W2161185495 @default.
- W4297997773 cites W2162089066 @default.
- W4297997773 cites W2174383334 @default.
- W4297997773 cites W2179479104 @default.