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- W4298002403 endingPage "2138" @default.
- W4298002403 startingPage "2138" @default.
- W4298002403 abstract "Human papillomaviruses (HPVs) cause a substantial amount of human disease from benign disease such as warts to malignant cancers including cervical carcinoma, head and neck cancer, and non-melanoma skin cancer. Our ability to model HPV-induced malignant disease has been impeded by species specific barriers and pre-clinical animal models have been challenging to develop. The recent discovery of a murine papillomavirus, MmuPV1, that infects laboratory mice and causes the same range of malignancies caused by HPVs provides the papillomavirus field the opportunity to test mechanistic hypotheses in a genetically manipulatable laboratory animal species in the context of natural infections. The E6 and E7 proteins encoded by high-risk HPVs, which are the HPV genotypes associated with human cancers, are multifunctional proteins that contribute to HPV-induced cancers in multiple ways. In this review, we describe the known activities of the MmuPV1-encoded E6 and E7 proteins and how those activities relate to the activities of HPV E6 and E7 oncoproteins encoded by mucosal and cutaneous high-risk HPV genotypes." @default.
- W4298002403 created "2022-10-01" @default.
- W4298002403 creator A5001039737 @default.
- W4298002403 creator A5013916954 @default.
- W4298002403 creator A5015582793 @default.
- W4298002403 date "2022-09-28" @default.
- W4298002403 modified "2023-09-26" @default.
- W4298002403 title "Molecular Mechanisms of MmuPV1 E6 and E7 and Implications for Human Disease" @default.
- W4298002403 cites W121685631 @default.
- W4298002403 cites W140061535 @default.
- W4298002403 cites W1492557824 @default.
- W4298002403 cites W1522666032 @default.
- W4298002403 cites W1522994879 @default.
- W4298002403 cites W1528169750 @default.
- W4298002403 cites W1529655352 @default.
- W4298002403 cites W1540836883 @default.
- W4298002403 cites W1550991491 @default.
- W4298002403 cites W1557998194 @default.
- W4298002403 cites W1570361865 @default.
- W4298002403 cites W1573394606 @default.
- W4298002403 cites W1574596120 @default.
- W4298002403 cites W1614632633 @default.
- W4298002403 cites W1673684449 @default.
- W4298002403 cites W1675517407 @default.
- W4298002403 cites W1675635349 @default.
- W4298002403 cites W1717839873 @default.
- W4298002403 cites W1726125699 @default.
- W4298002403 cites W1782055207 @default.
- W4298002403 cites W1831319429 @default.
- W4298002403 cites W183360374 @default.
- W4298002403 cites W189261120 @default.
- W4298002403 cites W1893993924 @default.
- W4298002403 cites W1898954837 @default.
- W4298002403 cites W190015672 @default.
- W4298002403 cites W1904002463 @default.
- W4298002403 cites W1940000718 @default.
- W4298002403 cites W1955283045 @default.
- W4298002403 cites W1966676297 @default.
- W4298002403 cites W1966761882 @default.
- W4298002403 cites W1968268590 @default.
- W4298002403 cites W1968285394 @default.
- W4298002403 cites W1972616341 @default.
- W4298002403 cites W1973403604 @default.
- W4298002403 cites W1974996818 @default.
- W4298002403 cites W1975136220 @default.
- W4298002403 cites W1976220823 @default.
- W4298002403 cites W1979476737 @default.
- W4298002403 cites W1979627083 @default.
- W4298002403 cites W1981726005 @default.
- W4298002403 cites W1985531401 @default.
- W4298002403 cites W1985884010 @default.
- W4298002403 cites W1990993212 @default.
- W4298002403 cites W1992235627 @default.
- W4298002403 cites W1994240672 @default.
- W4298002403 cites W1994353590 @default.
- W4298002403 cites W1994817833 @default.
- W4298002403 cites W1995039462 @default.
- W4298002403 cites W1996297294 @default.
- W4298002403 cites W1999931005 @default.
- W4298002403 cites W2007051294 @default.
- W4298002403 cites W2007749864 @default.
- W4298002403 cites W2014418134 @default.
- W4298002403 cites W2015840556 @default.
- W4298002403 cites W2016774481 @default.
- W4298002403 cites W2017517248 @default.
- W4298002403 cites W2017916074 @default.
- W4298002403 cites W2018646351 @default.
- W4298002403 cites W2019717333 @default.
- W4298002403 cites W2020553511 @default.
- W4298002403 cites W2020789898 @default.
- W4298002403 cites W2025145004 @default.
- W4298002403 cites W2026260312 @default.
- W4298002403 cites W2031841054 @default.
- W4298002403 cites W2033628308 @default.
- W4298002403 cites W2033725642 @default.
- W4298002403 cites W2034817571 @default.
- W4298002403 cites W2038500217 @default.
- W4298002403 cites W2039382131 @default.
- W4298002403 cites W2046182783 @default.
- W4298002403 cites W2050829000 @default.
- W4298002403 cites W2053249188 @default.
- W4298002403 cites W2053440993 @default.
- W4298002403 cites W2056379269 @default.
- W4298002403 cites W2056909284 @default.
- W4298002403 cites W2060786724 @default.
- W4298002403 cites W2063986051 @default.
- W4298002403 cites W2064851368 @default.
- W4298002403 cites W2066332001 @default.
- W4298002403 cites W2067697669 @default.
- W4298002403 cites W2072061578 @default.
- W4298002403 cites W2074252457 @default.
- W4298002403 cites W2074838903 @default.
- W4298002403 cites W2078066154 @default.
- W4298002403 cites W2080675024 @default.
- W4298002403 cites W2081881255 @default.
- W4298002403 cites W2083249050 @default.
- W4298002403 cites W2084344333 @default.
- W4298002403 cites W2085540051 @default.