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- W4298009268 abstract "To evaluate the properties of a single question to determine patient perception of remission and disease activity; to compare this with existing definitions for remission and low disease activity (LDA).Single-center, cross-sectional study in a tertiary care hospital. Patients with axSpA (fulfilling ASAS criteria) were consecutively included. Both the patient's perception of remission and LDA and that of the physician were evaluated with a single question. Agreement between the patients’ perception and other current definitions was tested using the prevalence-adjusted and bias-adjusted kappa (PABAK). The sensitivity (S) and specificity (Sp) of current definitions of disease states were tested against the patient's perception as the gold standard.The study population included 105 axSpA patients (63.8% males; 67.6% with radiographic sacroiliitis). Patients considered themselves to be in remission in 21% of cases and in LDA in 51.4%; physicians considered patients to be in remission in 45.7% of cases and in LDA in 35.2%. The poorest agreement was recorded for the patient's and the physician's perception of remission. The best agreement for patients’ perception of remission was for a BASDAI < 2 and normal C-reactive protein values. This definition was also the most sensitive (S = 72.7%) and specific (Sp = 83.1%) when the patient's perception was taken as the gold standard.In a real-life setting, the evaluation of remission by the patient through a single question was the hardest criterion to achieve, although it did prove to be a feasible, valid, and specific way to assess remission." @default.
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- W4298009268 date "2023-01-01" @default.
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- W4298009268 title "The updated GRAPPA and EULAR recommendations for the management of psoriatic arthritis: Similarities and differences" @default.
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- W4298009268 doi "https://doi.org/10.1016/j.jbspin.2022.105469" @default.
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