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- W4298109112 endingPage "1545" @default.
- W4298109112 startingPage "1507" @default.
- W4298109112 abstract "Crataegus pinnatifida (C. pinnatifida), including C. pinnatifida Bge. and its variant C. pinnatifida Bge. var. major N, E. Br., has traditionally been used as a homologous plant for traditional medicine and food in ethnic medical systems in China. Crataegus pinnatifida, especially its fruit, has been used for more than 2000 years to treat indigestion, stagnation of meat, hyperlipidemia, blood stasis, heart tingling, sores, etc. This review aimed to provide a systematic summary on the botany, traditional uses, phytochemistry, pharmacology and clinical applications of C. pinnatifida.This plant contains flavonoids, phenylpropanoids, terpenoids, organic acids, saccharides and essential oils. Experimental studies showed that it has hypolipidemic, antimyocardial, anti-ischemia, antithrombotic, anti-atherosclerotic, anti-inflammatory, antineoplastic neuroprotective activity, etc. Importantly, it has good effects in treating diseases of the digestive system and cardiovascular and cerebrovascular systems.There is convincing evidence from both in vitro and in vivo studies supporting the traditional uses of C. pinnatifida. However, multitarget network pharmacology and molecular docking technology should be used to study the interaction between the active ingredients and targets of C. pinnatifida. Furthermore, exploring the synergy of C. pinnatifida with other Chinese medicines to provide new understanding of complex diseases may be a promising strategy." @default.
- W4298109112 created "2022-10-01" @default.
- W4298109112 creator A5001650819 @default.
- W4298109112 creator A5017926403 @default.
- W4298109112 creator A5024788820 @default.
- W4298109112 creator A5047713923 @default.
- W4298109112 creator A5064293717 @default.
- W4298109112 creator A5086842889 @default.
- W4298109112 date "2022-09-30" @default.
- W4298109112 modified "2023-10-14" @default.
- W4298109112 title "Botany, traditional uses, phytochemistry and pharmacological activity of <i>Crataegus pinnatifida</i> (Chinese hawthorn): a review" @default.
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