Matches in SemOpenAlex for { <https://semopenalex.org/work/W4298118220> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4298118220 endingPage "304" @default.
- W4298118220 startingPage "300" @default.
- W4298118220 abstract "The freezing effect on peptide coupling in organic solutions of different polarity has been investigated and compared with the results obtained in liquid phase. The model reaction of DCC-activated coupling of Boc-Ala-Phe-OH with H-Ala-OBut has been carried out in dioxane, dimethylsulfoxide and formamide, as well as in mixtures (90%/10%, v/v) of dioxane with acetonitrile, dimethylformamide, dimethylsulfoxide and formamide. The reactions have been traced and evaluated by RP-HPLC analysis. Freezing the reaction mixture resulted in all cases in a significant suppression of the N-dipeptidylurea side-product formation together with a slight decrease of tripeptide epimerization. The coupling yields and the side effects depended on the solvent, with the dioxane and dioxane/acetonitrile mixture produced the best results. The role of freezing and solvent in the improved results is discussed. © 1998 European Peptide Society and John Wiley & Sons, Ltd." @default.
- W4298118220 created "2022-10-01" @default.
- W4298118220 creator A5004908128 @default.
- W4298118220 creator A5019816528 @default.
- W4298118220 creator A5066592633 @default.
- W4298118220 date "1998-06-01" @default.
- W4298118220 modified "2023-10-18" @default.
- W4298118220 title "Cryochemistry: freezing effect on peptide coupling in different organic solutions" @default.
- W4298118220 cites W1553227889 @default.
- W4298118220 cites W1992501379 @default.
- W4298118220 cites W2022988521 @default.
- W4298118220 cites W2029411504 @default.
- W4298118220 cites W2045276835 @default.
- W4298118220 cites W2052544098 @default.
- W4298118220 cites W2060558860 @default.
- W4298118220 cites W2090391132 @default.
- W4298118220 cites W2134062327 @default.
- W4298118220 cites W2332831250 @default.
- W4298118220 doi "https://doi.org/10.1002/(sici)1099-1387(199806)4:4<300::aid-psc148>3.0.co;2-i" @default.
- W4298118220 hasPublicationYear "1998" @default.
- W4298118220 type Work @default.
- W4298118220 citedByCount "5" @default.
- W4298118220 countsByYear W42981182202012 @default.
- W4298118220 countsByYear W42981182202020 @default.
- W4298118220 countsByYear W42981182202021 @default.
- W4298118220 crossrefType "journal-article" @default.
- W4298118220 hasAuthorship W4298118220A5004908128 @default.
- W4298118220 hasAuthorship W4298118220A5019816528 @default.
- W4298118220 hasAuthorship W4298118220A5066592633 @default.
- W4298118220 hasConcept C132439834 @default.
- W4298118220 hasConcept C155647269 @default.
- W4298118220 hasConcept C161790260 @default.
- W4298118220 hasConcept C167392928 @default.
- W4298118220 hasConcept C178790620 @default.
- W4298118220 hasConcept C179998833 @default.
- W4298118220 hasConcept C185592680 @default.
- W4298118220 hasConcept C203130289 @default.
- W4298118220 hasConcept C2777463227 @default.
- W4298118220 hasConcept C2777712214 @default.
- W4298118220 hasConcept C2778270854 @default.
- W4298118220 hasConcept C2779281246 @default.
- W4298118220 hasConcept C2780471494 @default.
- W4298118220 hasConcept C2993921914 @default.
- W4298118220 hasConcept C43617362 @default.
- W4298118220 hasConcept C48424934 @default.
- W4298118220 hasConcept C55493867 @default.
- W4298118220 hasConceptScore W4298118220C132439834 @default.
- W4298118220 hasConceptScore W4298118220C155647269 @default.
- W4298118220 hasConceptScore W4298118220C161790260 @default.
- W4298118220 hasConceptScore W4298118220C167392928 @default.
- W4298118220 hasConceptScore W4298118220C178790620 @default.
- W4298118220 hasConceptScore W4298118220C179998833 @default.
- W4298118220 hasConceptScore W4298118220C185592680 @default.
- W4298118220 hasConceptScore W4298118220C203130289 @default.
- W4298118220 hasConceptScore W4298118220C2777463227 @default.
- W4298118220 hasConceptScore W4298118220C2777712214 @default.
- W4298118220 hasConceptScore W4298118220C2778270854 @default.
- W4298118220 hasConceptScore W4298118220C2779281246 @default.
- W4298118220 hasConceptScore W4298118220C2780471494 @default.
- W4298118220 hasConceptScore W4298118220C2993921914 @default.
- W4298118220 hasConceptScore W4298118220C43617362 @default.
- W4298118220 hasConceptScore W4298118220C48424934 @default.
- W4298118220 hasConceptScore W4298118220C55493867 @default.
- W4298118220 hasIssue "4" @default.
- W4298118220 hasLocation W42981182201 @default.
- W4298118220 hasOpenAccess W4298118220 @default.
- W4298118220 hasPrimaryLocation W42981182201 @default.
- W4298118220 hasRelatedWork W1580149691 @default.
- W4298118220 hasRelatedWork W1980528289 @default.
- W4298118220 hasRelatedWork W1981124710 @default.
- W4298118220 hasRelatedWork W2043575866 @default.
- W4298118220 hasRelatedWork W2046162595 @default.
- W4298118220 hasRelatedWork W2050831462 @default.
- W4298118220 hasRelatedWork W2115651657 @default.
- W4298118220 hasRelatedWork W2154600008 @default.
- W4298118220 hasRelatedWork W2313147062 @default.
- W4298118220 hasRelatedWork W4235953902 @default.
- W4298118220 hasVolume "4" @default.
- W4298118220 isParatext "false" @default.
- W4298118220 isRetracted "false" @default.
- W4298118220 workType "article" @default.