FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4298619636> ?p ?o ?g. }

• W4298619636 endingPage "396" @default.
• W4298619636 startingPage "394" @default.
• W4298619636 abstract "Engagement in sun protection behaviors is broadly recommended to prevent the development of Ultraviolet radiation (UVR)-related conditions such as skin cancer.1 These behaviors may come in the form of sun avoidance, the use of protective clothing, and application of sunscreen. Weighing the risks and benefits of sun exposure is a particularly important consideration in sunburn-susceptible Caucasian populations as overlap in the International Commission on Illumination action spectra of erythema with that of pre-vitamin D synthesis generates concern for sunscreen use compromising vitamin D synthesis.2, 3 There are mixed reports on the impact of sun protection behaviors and their influence on vitamin D status.4, 5 Vitamin D deficiency is associated with an increased risk of bone fractures, autoimmune disease, and cancer; however, supplementation may manage vitamin D deficiency while promoting sun protection habits, though the literature to support such an effort is unclear.6 Our study aims to investigate the relationship between engagement in sun protection behaviors and vitamin D deficiency using serum 25-hydroxyvitamin D data from the 2013 to 2018 US National Health and Nutrition Examination Surveys (NHANES). Our investigation sourced data from the 2013 to 2018 cycles of the NHANES, which collects nationally representative health data pertaining to the civilian, non-institutionalized population of the United States in 2-year intervals.7 Non-Hispanic White respondents who underwent the laboratory examination and provided valid responses to items in the dermatology questionnaire and dietary interview were included in the study. Sun protection behaviors were evaluated through the questionnaires: staying in the shade, wearing long-sleeved shirts, and using sunscreen. Participants' engagement in these behaviors was classified as “frequent” when reported as “always” or “most of the time,” as “occasional” when reported as “sometimes” or “rarely,” and as “never” when no engagement was reported. Dietary interview responses were used to measure vitamin D supplementation (μg) over a 30-day period. Liquid chromatography–tandem mass spectrometry was used to measure serum 25(OH)D levels for each participant. The season of each participant's interview was recorded as 6-month time periods: November 1–April 30 or May 1–October 31. Demographic data were also collected. As the NHANES reports publicly accessible de-identified data, institutional review board approval was not required. Informed consent was obtained when the data was originally collected. A cross-sectional analysis was conducted based on responses to the NHANES dermatology questionnaire, dietary interview, and laboratory data. The sample was weighted to account for the complex survey design of the NHANES, accounting for oversampling, nonresponse, and post-stratification adjustment to match population control totals from the US Census Bureau. All analyses were informed by the analytic guidelines published by the CDC.8 The primary outcome measure of vitamin D deficiency was defined as 25(OH)D concentration <50 nmol/L. Multiple logistic regression models assessed the odds of vitamin D deficiency after adjusting for age, race, gender, vitamin D supplementation, and season of the laboratory examination. Adjusted odds ratios, 95% confidence intervals, and p-values were computed from the multiple logistic regression models. A priori significance was set at p < .05. A total of 1213 participants met the inclusion criteria for the study. The weighted sample was more commonly female (54.9%), aged 43.1 years, and occasionally engaged in sunscreen use (44.4%), wearing long-sleeved shirts (53.9%), and staying in the shade (67.8%). Sample demographics are reported in Table 1. Wearing long-sleeved shirts was significantly associated with vitamin D deficiency (aOR = 3.32; 95% CI: 1.26–8.76; p = .017), though no other forms of sun protection demonstrated similar odds. Vitamin D supplementation >20 μg over a 30-day period reduced the odds of vitamin D deficiency (aOR = 0.33; 95% CI: 0.13–0.81; p = .018). Participants interviewed between May 1 and October 31 were less likely to be vitamin D deficient (aOR = 0.28; 95% CI: 0.13–0.57; p = .001). Weighted odds of vitamin D deficiency are reported in Table 2. Engagement in sun protection behaviors was not associated with vitamin D deficiency when accounting for vitamin D supplement intake, with the exception of frequently wearing long-sleeve clothing. Limitations in sample size, seasonal impact being limited to 6-month periods, and inconsistencies in individual sun protection practices contribute to variations in UVR exposure. Our findings suggest no direct linkage between sun protection and vitamin D health in non-Hispanic white US adults, offering encouraging evidence to contribute to the growing body of literature supporting sun-protective practices. As such, providers should aim to recommend sun protection alongside vitamin D supplementation to prevent the development of UVR-related conditions and maintain optimal health among patients. SP, SP, RMS, SD, and SS report no conflicts of interest. PAL reports research grants/funding from the National Eczema Association, AOBiome, Regeneron/Sanofi Genzyme, and AbbVie; is on the speaker's bureau for Regeneron/Sanofi Genzyme, Pfizer, Incyte, Eli Lilly, LEO, Galderma, and L'Oreal; reports consulting/advisory boards for Almirall, ASLAN Pharmaceuticals, Dermavant, Regeneron/Sanofi Genzyme, Pfizer, LEO Pharmaceuticals, AbbVie, Eli Lilly, Micreos, L'Oreal, Pierre-Fabre, Johnson & Johnson, Level Ex, KPAway, Unilever, Menlo Therapeutics, Theraplex, IntraDerm, Exeltis, AOBiome, Realm Therapeutics, Altus Labs, Galderma, Verrica, Amyris, Bodewell, Burt's Bees, My-Or Diagnostics, and Kimberly-Clark. In addition, Dr. Lio has a patent pending for a Theraplex product with royalties paid and is a Board member and Scientific Advisory Committee Member of the National Eczema Association. IRB approval was not required as the study uses a publicly available data source with de-identified information." @default.
• W4298619636 created "2022-10-02" @default.
• W4298619636 creator A5000134388 @default.
• W4298619636 creator A5002501205 @default.
• W4298619636 creator A5013044943 @default.
• W4298619636 creator A5043179209 @default.
• W4298619636 creator A5048424331 @default.
• W4298619636 creator A5050368462 @default.
• W4298619636 date "2022-10-20" @default.
• W4298619636 modified "2023-10-14" @default.
• W4298619636 title "Effects of sun protection on serum vitamin D deficiency" @default.
• W4298619636 cites W1966724428 @default.
• W4298619636 cites W2077933143 @default.
• W4298619636 cites W2944340031 @default.
• W4298619636 cites W2999622127 @default.
• W4298619636 cites W3203390200 @default.
• W4298619636 cites W3207712644 @default.
• W4298619636 doi "https://doi.org/10.1111/phpp.12838" @default.
• W4298619636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36181727" @default.
• W4298619636 hasPublicationYear "2022" @default.
• W4298619636 type Work @default.
• W4298619636 citedByCount "0" @default.
• W4298619636 crossrefType "journal-article" @default.
• W4298619636 hasAuthorship W4298619636A5000134388 @default.
• W4298619636 hasAuthorship W4298619636A5002501205 @default.
• W4298619636 hasAuthorship W4298619636A5013044943 @default.
• W4298619636 hasAuthorship W4298619636A5043179209 @default.
• W4298619636 hasAuthorship W4298619636A5048424331 @default.
• W4298619636 hasAuthorship W4298619636A5050368462 @default.
• W4298619636 hasBestOaLocation W42986196361 @default.
• W4298619636 hasConcept C121608353 @default.
• W4298619636 hasConcept C124490489 @default.
• W4298619636 hasConcept C126322002 @default.
• W4298619636 hasConcept C16005928 @default.
• W4298619636 hasConcept C2776940978 @default.
• W4298619636 hasConcept C2777524492 @default.
• W4298619636 hasConcept C2777789703 @default.
• W4298619636 hasConcept C2779121184 @default.
• W4298619636 hasConcept C2779740938 @default.
• W4298619636 hasConcept C2779874844 @default.
• W4298619636 hasConcept C2908647359 @default.
• W4298619636 hasConcept C2994204100 @default.
• W4298619636 hasConcept C3017665839 @default.
• W4298619636 hasConcept C71924100 @default.
• W4298619636 hasConcept C99454951 @default.
• W4298619636 hasConceptScore W4298619636C121608353 @default.
• W4298619636 hasConceptScore W4298619636C124490489 @default.
• W4298619636 hasConceptScore W4298619636C126322002 @default.
• W4298619636 hasConceptScore W4298619636C16005928 @default.
• W4298619636 hasConceptScore W4298619636C2776940978 @default.
• W4298619636 hasConceptScore W4298619636C2777524492 @default.
• W4298619636 hasConceptScore W4298619636C2777789703 @default.
• W4298619636 hasConceptScore W4298619636C2779121184 @default.
• W4298619636 hasConceptScore W4298619636C2779740938 @default.
• W4298619636 hasConceptScore W4298619636C2779874844 @default.
• W4298619636 hasConceptScore W4298619636C2908647359 @default.
• W4298619636 hasConceptScore W4298619636C2994204100 @default.
• W4298619636 hasConceptScore W4298619636C3017665839 @default.
• W4298619636 hasConceptScore W4298619636C71924100 @default.
• W4298619636 hasConceptScore W4298619636C99454951 @default.
• W4298619636 hasIssue "4" @default.
• W4298619636 hasLocation W42986196361 @default.
• W4298619636 hasLocation W42986196362 @default.
• W4298619636 hasOpenAccess W4298619636 @default.
• W4298619636 hasPrimaryLocation W42986196361 @default.
• W4298619636 hasRelatedWork W1594348302 @default.
• W4298619636 hasRelatedWork W2059288347 @default.
• W4298619636 hasRelatedWork W2101726658 @default.
• W4298619636 hasRelatedWork W2159283629 @default.
• W4298619636 hasRelatedWork W2186210554 @default.
• W4298619636 hasRelatedWork W2344332853 @default.
• W4298619636 hasRelatedWork W2409002424 @default.
• W4298619636 hasRelatedWork W2948840654 @default.
• W4298619636 hasRelatedWork W4235560066 @default.
• W4298619636 hasRelatedWork W3094420955 @default.
• W4298619636 hasVolume "39" @default.
• W4298619636 isParatext "false" @default.
• W4298619636 isRetracted "false" @default.
• W4298619636 workType "article" @default.