FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4298621154> ?p ?o ?g. }

• W4298621154 endingPage "10" @default.
• W4298621154 startingPage "3" @default.
• W4298621154 abstract "Asthma is a syndrome with extremely diverse clinical phenotypes in which the onset, severity, and response to treatment are defined by the complex interplay of many genetic and environmental factors. Environmental factors epigenetically affect gene expression, and the disease is driven by a multidimensional dynamic network involving RNA and protein molecules derived from gene expression, as well as various metabolic products. In other words, specific pathophysiological mechanisms or endotypes are dynamic networks that arise in response to individual genotypes and the various environmental factors to which individuals have been exposed since before birth, such as diet, infection, air pollution, smoking, antibiotic use, and the bacterial flora of the intestinal tract, skin, and lungs. A key feature of asthma genome scans is their potential to reveal the molecular pathways that lead to pathogenesis. Endotypes that drive the disease have a significant impact on the phenotypes of asthma patients, including their drug responsiveness. Understanding endotypes will lead to not only the implementation of therapies that are tailored to the specific molecular network(s) underlying the patient's condition, but also to the development of therapeutic strategies that target individual endotypes, as well as to precision health, which will enable the prediction of disease onset with high accuracy from an early stage and the implementation of preventive strategies based on endotypes. Understanding of endotypes will pave the way for the practice of precision medicine in asthma care, moving away from ‘one-size-fits-all’ medicine and population-based prevention approaches that do not take individuals' susceptibility into account." @default.
• W4298621154 created "2022-10-02" @default.
• W4298621154 creator A5014676549 @default.
• W4298621154 date "2023-01-01" @default.
• W4298621154 modified "2023-09-26" @default.
• W4298621154 title "The understanding of asthma pathogenesis in the era of precision medicine" @default.
• W4298621154 cites W1637973003 @default.
• W4298621154 cites W1859222707 @default.
• W4298621154 cites W1981352040 @default.
• W4298621154 cites W1982646340 @default.
• W4298621154 cites W1991747007 @default.
• W4298621154 cites W1992622607 @default.
• W4298621154 cites W1992974787 @default.
• W4298621154 cites W1999970608 @default.
• W4298621154 cites W2001977610 @default.
• W4298621154 cites W2008599922 @default.
• W4298621154 cites W2012568595 @default.
• W4298621154 cites W2019966611 @default.
• W4298621154 cites W2021324933 @default.
• W4298621154 cites W2021579290 @default.
• W4298621154 cites W2021701428 @default.
• W4298621154 cites W2057192777 @default.
• W4298621154 cites W2060322569 @default.
• W4298621154 cites W2063014521 @default.
• W4298621154 cites W2072063345 @default.
• W4298621154 cites W2083559141 @default.
• W4298621154 cites W2084911228 @default.
• W4298621154 cites W2086857319 @default.
• W4298621154 cites W2089627898 @default.
• W4298621154 cites W2090051914 @default.
• W4298621154 cites W2102687347 @default.
• W4298621154 cites W2106065407 @default.
• W4298621154 cites W2106715003 @default.
• W4298621154 cites W2108919922 @default.
• W4298621154 cites W2109755061 @default.
• W4298621154 cites W2109989887 @default.
• W4298621154 cites W2114695306 @default.
• W4298621154 cites W2119016887 @default.
• W4298621154 cites W2121739711 @default.
• W4298621154 cites W2122819603 @default.
• W4298621154 cites W2142846533 @default.
• W4298621154 cites W2147655543 @default.
• W4298621154 cites W2150035260 @default.
• W4298621154 cites W2154263136 @default.
• W4298621154 cites W2157710399 @default.
• W4298621154 cites W2158206794 @default.
• W4298621154 cites W2194674866 @default.
• W4298621154 cites W2238181656 @default.
• W4298621154 cites W2263808047 @default.
• W4298621154 cites W2269263380 @default.
• W4298621154 cites W2405917170 @default.
• W4298621154 cites W2416251794 @default.
• W4298621154 cites W2418464944 @default.
• W4298621154 cites W2516346419 @default.
• W4298621154 cites W2528730307 @default.
• W4298621154 cites W2542623541 @default.
• W4298621154 cites W2594108584 @default.
• W4298621154 cites W2597217850 @default.
• W4298621154 cites W2606047052 @default.
• W4298621154 cites W2611050494 @default.
• W4298621154 cites W2611844791 @default.
• W4298621154 cites W2614615141 @default.
• W4298621154 cites W2755116403 @default.
• W4298621154 cites W2766840788 @default.
• W4298621154 cites W2910127585 @default.
• W4298621154 cites W2921081399 @default.
• W4298621154 cites W2921494130 @default.
• W4298621154 cites W2921533322 @default.
• W4298621154 cites W2944297063 @default.
• W4298621154 cites W2958012222 @default.
• W4298621154 cites W2961190502 @default.
• W4298621154 cites W2965540528 @default.
• W4298621154 cites W2972324731 @default.
• W4298621154 cites W2992115024 @default.
• W4298621154 cites W3000256966 @default.
• W4298621154 cites W3008501394 @default.
• W4298621154 cites W3015651558 @default.
• W4298621154 cites W3026310174 @default.
• W4298621154 cites W3026474798 @default.
• W4298621154 cites W3039000161 @default.
• W4298621154 cites W3040085018 @default.
• W4298621154 cites W3048677773 @default.
• W4298621154 cites W3092564396 @default.
• W4298621154 cites W3133204522 @default.
• W4298621154 cites W3134224893 @default.
• W4298621154 cites W3158976928 @default.
• W4298621154 cites W3161654895 @default.
• W4298621154 cites W3195804343 @default.
• W4298621154 cites W3201004089 @default.
• W4298621154 cites W3206486794 @default.
• W4298621154 cites W402335930 @default.
• W4298621154 cites W4206612177 @default.
• W4298621154 cites W4221061999 @default.
• W4298621154 doi "https://doi.org/10.1016/j.alit.2022.09.001" @default.
• W4298621154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36195530" @default.
• W4298621154 hasPublicationYear "2023" @default.
• W4298621154 type Work @default.
• W4298621154 citedByCount "6" @default.

• next