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- W4299352205 abstract "Objective: Anxiety is characterized by psychologically affected abnormal cognitive, somatic, emotional, and behavioral components. Anxiety is usually a normal reaction to stress in day to day life. But, when it becomes excessive, it comes under anxiety disorder. Commonly benzodiazepines (BZDs) are the major class of drugs used in anxiety and related disorders but, long-term use of the same may cause many adverse psychological and physical effects which vary from mild to severe. The objective of our study was to evaluate the chronic anxiolytic effect of Ethanolic Extract of Saraca asoca Bark (EESAB) in Wistar Albino Rats. Material and Methods: The rats weighing 150–200 gm were divided into 5 groups containing 6 animals for each dose and were housed for 10 days prior to testing. In this study, control (1% Gum acacia), test drug EESAB (100, 200 & 400 mg/ kg) and standard drug Diazepam (1.0 mg/kg) were administered orally once a day for ten days and one hour before the experiment on tenth day. Experiments were conducted by Elevated Plus Maze (EPM). Results and Conclusions: Our results suggest that, behavioral disinhibitory effects of EESAB exhibited chronic anxiolytic activity at the dose of 200 and 400 mg/kg compared to control." @default.
- W4299352205 created "2022-10-02" @default.
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- W4299352205 date "2014-04-25" @default.
- W4299352205 modified "2023-09-25" @default.
- W4299352205 title "Chronic anxiolytic activity of ethanolic extract of Saraca asoca bark in wistar albino rats" @default.
- W4299352205 doi "https://doi.org/10.31254/jsir.2014.3211" @default.
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