Matches in SemOpenAlex for { <https://semopenalex.org/work/W4299785579> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4299785579 abstract "The αvβ3 integrin is a heterodimeric adhesion molecule involved in tumor cell migration and angiogenesis. The integrin is overexpressed in angiogenic tumor endothelial cells, where it typically has a low concentration. This specific expression of αvβ3 makes it a valid biomarker for antiangiogenic and imaging drugs. As a functional imaging modality, positron emission tomography (PET) provides information about biochemical and physiological changes in vivo, due to its unique high sensitivity at the nanomolar scale. Hence, radiometal-based PET radiopharmaceuticals have received great attention for the non-invasive quantification of tumor angiogenesis. This paper provides a systemic protocol to prepare a new radiometal-labeled peptide for the evaluation of angiogenesis. This protocol contains information about radiochemical reliability, lipophilicity, cell uptake, serum stability, and pharmacokinetic properties. The 68Ga-RGD-peptide is one of the representative PET ligands toward αvβ3 integrin. Here, we introduce a protocol to prepare a 68Ga-RGD-peptide and the evaluation of its biological efficacy." @default.
- W4299785579 created "2022-10-03" @default.
- W4299785579 creator A5009204601 @default.
- W4299785579 creator A5013033476 @default.
- W4299785579 creator A5013563942 @default.
- W4299785579 creator A5033256758 @default.
- W4299785579 creator A5071674449 @default.
- W4299785579 creator A5074289440 @default.
- W4299785579 date "2019-01-07" @default.
- W4299785579 modified "2023-09-24" @default.
- W4299785579 title "Preparing a <sup>68</sup>Ga-labeled Arginine Glycine Aspartate (RGD)-peptide for Angiogenesis" @default.
- W4299785579 doi "https://doi.org/10.3791/58218-v" @default.
- W4299785579 hasPublicationYear "2019" @default.
- W4299785579 type Work @default.
- W4299785579 citedByCount "0" @default.
- W4299785579 crossrefType "journal-article" @default.
- W4299785579 hasAuthorship W4299785579A5009204601 @default.
- W4299785579 hasAuthorship W4299785579A5013033476 @default.
- W4299785579 hasAuthorship W4299785579A5013563942 @default.
- W4299785579 hasAuthorship W4299785579A5033256758 @default.
- W4299785579 hasAuthorship W4299785579A5071674449 @default.
- W4299785579 hasAuthorship W4299785579A5074289440 @default.
- W4299785579 hasConcept C136339569 @default.
- W4299785579 hasConcept C1491633281 @default.
- W4299785579 hasConcept C150903083 @default.
- W4299785579 hasConcept C185592680 @default.
- W4299785579 hasConcept C195687474 @default.
- W4299785579 hasConcept C207001950 @default.
- W4299785579 hasConcept C2777756961 @default.
- W4299785579 hasConcept C2779281246 @default.
- W4299785579 hasConcept C2780394083 @default.
- W4299785579 hasConcept C502942594 @default.
- W4299785579 hasConcept C515207424 @default.
- W4299785579 hasConcept C55493867 @default.
- W4299785579 hasConcept C86803240 @default.
- W4299785579 hasConcept C95444343 @default.
- W4299785579 hasConceptScore W4299785579C136339569 @default.
- W4299785579 hasConceptScore W4299785579C1491633281 @default.
- W4299785579 hasConceptScore W4299785579C150903083 @default.
- W4299785579 hasConceptScore W4299785579C185592680 @default.
- W4299785579 hasConceptScore W4299785579C195687474 @default.
- W4299785579 hasConceptScore W4299785579C207001950 @default.
- W4299785579 hasConceptScore W4299785579C2777756961 @default.
- W4299785579 hasConceptScore W4299785579C2779281246 @default.
- W4299785579 hasConceptScore W4299785579C2780394083 @default.
- W4299785579 hasConceptScore W4299785579C502942594 @default.
- W4299785579 hasConceptScore W4299785579C515207424 @default.
- W4299785579 hasConceptScore W4299785579C55493867 @default.
- W4299785579 hasConceptScore W4299785579C86803240 @default.
- W4299785579 hasConceptScore W4299785579C95444343 @default.
- W4299785579 hasIssue "143" @default.
- W4299785579 hasLocation W42997855791 @default.
- W4299785579 hasOpenAccess W4299785579 @default.
- W4299785579 hasPrimaryLocation W42997855791 @default.
- W4299785579 hasRelatedWork W1979558627 @default.
- W4299785579 hasRelatedWork W2013166677 @default.
- W4299785579 hasRelatedWork W2033837643 @default.
- W4299785579 hasRelatedWork W2054330160 @default.
- W4299785579 hasRelatedWork W2101363876 @default.
- W4299785579 hasRelatedWork W2134628893 @default.
- W4299785579 hasRelatedWork W2205815429 @default.
- W4299785579 hasRelatedWork W2935701384 @default.
- W4299785579 hasRelatedWork W4214558002 @default.
- W4299785579 hasRelatedWork W4313380908 @default.
- W4299785579 isParatext "false" @default.
- W4299785579 isRetracted "false" @default.
- W4299785579 workType "article" @default.