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- W4300018181 abstract "Abstract Nitrofurantoin is presently used as an antibacterial agent for the urinary tract of both man and animals. A new, quantitative procedure for the determination of this drug in urine consists of direct extraction of the nonionized form of the drug by the use of nitromethane, addition of an alkaline reagent to the extract to produce a visible color, and determination of the nitrofurantoin concentration by spectrophotometry. The method has a sensitivity of 5 mg./L., with recoveries of 99-101% and a standard curve that is linear to 100 mg./L. Results indicate that the method measures nitrofurantoin alone, and not its metabolites, in rat, dog, and human urine." @default.
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- W4300018181 date "1965-10-01" @default.
- W4300018181 modified "2023-10-17" @default.
- W4300018181 title "A New Method for the Determination of Nitrofurantoin in Urine" @default.
- W4300018181 doi "https://doi.org/10.1093/clinchem/11.10.925" @default.
- W4300018181 hasPublicationYear "1965" @default.
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