Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300158575> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W4300158575 abstract "Ocular surface (OS) consists of an epithelial sheet with three connected parts: palpebral conjunctiva, bulbar conjunctiva and corneal epithelium. Disruption of OS would lead to keratitis, conjunctivitis or both (keratoconjunctivitis). In experimental animal models with certain genetic modifications or artificial operations, it is useful to examine all parts of the OS epithelial sheet to evaluate relative pathogenetic changes of each part in parallel. However, dissection of OS tissue as a whole without distortion or damage has been challenging, primarily due to the softness and thinness of the OS affixed to physically separate yet movable eyelids and eyeball. Additionally, the deep eye socket formed by the hard skull/orbital bones is fully occupied by the eyeball leaving limited space for operating dissections. As a result, direct dissection of the eyeball with associated OS tissues from the facial side would often lead to tissue damages, especially the palpebral and bulbar conjunctiva. In this protocol, we described a method to remove the skull and orbital bones sequentially from a bisected mouse head, leaving eyelids, ocular surface, lens and retina altogether in one piece. The integrity of the OS sheet was well preserved and could be examined by histology or immunostaining in a single section." @default.
- W4300158575 created "2022-10-03" @default.
- W4300158575 creator A5032950222 @default.
- W4300158575 creator A5044174169 @default.
- W4300158575 date "2019-10-20" @default.
- W4300158575 modified "2023-09-30" @default.
- W4300158575 title "Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry" @default.
- W4300158575 doi "https://doi.org/10.3791/60086-v" @default.
- W4300158575 hasPublicationYear "2019" @default.
- W4300158575 type Work @default.
- W4300158575 citedByCount "0" @default.
- W4300158575 crossrefType "journal-article" @default.
- W4300158575 hasAuthorship W4300158575A5032950222 @default.
- W4300158575 hasAuthorship W4300158575A5044174169 @default.
- W4300158575 hasConcept C105702510 @default.
- W4300158575 hasConcept C118487528 @default.
- W4300158575 hasConcept C142724271 @default.
- W4300158575 hasConcept C204232928 @default.
- W4300158575 hasConcept C2775862295 @default.
- W4300158575 hasConcept C2775984611 @default.
- W4300158575 hasConcept C2776882836 @default.
- W4300158575 hasConcept C2779300802 @default.
- W4300158575 hasConcept C4224716 @default.
- W4300158575 hasConcept C42558546 @default.
- W4300158575 hasConcept C57742111 @default.
- W4300158575 hasConcept C71924100 @default.
- W4300158575 hasConcept C86803240 @default.
- W4300158575 hasConceptScore W4300158575C105702510 @default.
- W4300158575 hasConceptScore W4300158575C118487528 @default.
- W4300158575 hasConceptScore W4300158575C142724271 @default.
- W4300158575 hasConceptScore W4300158575C204232928 @default.
- W4300158575 hasConceptScore W4300158575C2775862295 @default.
- W4300158575 hasConceptScore W4300158575C2775984611 @default.
- W4300158575 hasConceptScore W4300158575C2776882836 @default.
- W4300158575 hasConceptScore W4300158575C2779300802 @default.
- W4300158575 hasConceptScore W4300158575C4224716 @default.
- W4300158575 hasConceptScore W4300158575C42558546 @default.
- W4300158575 hasConceptScore W4300158575C57742111 @default.
- W4300158575 hasConceptScore W4300158575C71924100 @default.
- W4300158575 hasConceptScore W4300158575C86803240 @default.
- W4300158575 hasIssue "152" @default.
- W4300158575 hasLocation W43001585751 @default.
- W4300158575 hasOpenAccess W4300158575 @default.
- W4300158575 hasPrimaryLocation W43001585751 @default.
- W4300158575 hasRelatedWork W11782750 @default.
- W4300158575 hasRelatedWork W1572223735 @default.
- W4300158575 hasRelatedWork W2072924589 @default.
- W4300158575 hasRelatedWork W21216306 @default.
- W4300158575 hasRelatedWork W2171714371 @default.
- W4300158575 hasRelatedWork W2441699696 @default.
- W4300158575 hasRelatedWork W2555652867 @default.
- W4300158575 hasRelatedWork W3086192810 @default.
- W4300158575 hasRelatedWork W4245650736 @default.
- W4300158575 hasRelatedWork W85560277 @default.
- W4300158575 isParatext "false" @default.
- W4300158575 isRetracted "false" @default.
- W4300158575 workType "article" @default.