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- W4300186700 abstract "The conventional sequencing method has limitations in throughput, scalability, and speed. To overcome these, next-generation sequencing (NGS) can enable high throughput decoding of deoxyribonucleic acid (DNA) molecules up to the scale of the entire human genome. The Illumina/Solexa Genome Analyzer platform is an example of NGS technology, which can sequence in parallel many adaptor flanked fragments up to several hundred base pairs in length. The Helicos Genetic Analysis System is similar to Illumina in that it performs sequencing based on single nucleotide addition. The Ion Torrent chip technology is also based on the sequencing by synthesis method, during which a complementary strand is built based on the sequence of a template strand. NGS technologies enable high-throughput decoding of DNA molecules up to the entire human genome, and allow highly multiplexed and parallel sequencing, which overcomes conventional sequencing's limitations in throughput, scalability, and speed." @default.
- W4300186700 created "2022-10-03" @default.
- W4300186700 date "2022-08-10" @default.
- W4300186700 modified "2023-09-27" @default.
- W4300186700 title "Next‐Generation Sequencing and FET‐Based Biochips" @default.
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- W4300186700 doi "https://doi.org/10.1002/9781118910573.ch7" @default.
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