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- W4300466406 abstract "The differences in remodeling among frozen allografts, frozen autografts, and fresh autografts were investigated using a patellar tendon transplantation model in 2 different strains of rats. In this study, isografting (transplantation among the same strain inbred animals) was adopted as an autograft model. This method makes it possible to set up a frozen autograft model. Evaluation included mechanical properties determined during tensile failure tests, cross sectional area, histologic findings, and collagen fibril distribution. Recipient rats were euthanized at 4, 8, 12, and 24 weeks after transplantation (n = 5, in each group and in each period). The frozen allografts showed significantly less tensile strength than did the frozen autografts at 4 weeks, but this difference was transient and diminished by 8 weeks. The tensile strength of the fresh autografts was significantly greater than that of the frozen autografts at 8 weeks or the frozen allografts at 8 and 12 weeks. It was suggested that freeze thawing has adverse effects on the remodeling of fresh autografts in this extraarticular graft model. The cross sectional area for each type of graft at each posttransplantation period was about twice as large as that before transplantation. The collagen fibril profile of the frozen allografts was similar to that of the frozen autografts. However, the fresh autografts showed a greater number of large diameter fibrils and a lesser number of small diameter fibrils than did the other 2 frozen groups." @default.
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- W4300466406 date "1997-02-01" @default.
- W4300466406 modified "2023-09-25" @default.
- W4300466406 title "Remodeling of Allogeneic and Autogenous Patellar Tendon Grafts in Rats" @default.
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- W4300466406 doi "https://doi.org/10.1097/00003086-199702000-00032" @default.
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