FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300550988> ?p ?o ?g. }

• W4300550988 endingPage "115" @default.
• W4300550988 startingPage "103" @default.
• W4300550988 abstract "In the white-opaque transition, cells of Candida albicans strain WO-1 switch reversibly and at high frequency between phases which differ both in colony and cellular phenotype. The lipid and sterol contents of the two phases were compared. White cells were higher in lipid and sterol contents in both mid-exponential and stationary phase cultures. In mid-exponential phase cultures, the lipids of white cells accumulated substantial amounts of apolar compounds, including steryl esters, alkyl esters, triacylglycerols, fatty acids, free sterols and mono- and di-glycerides, while opaque cells accumulated nearly equal proportions of apolar and polar compounds, mainly phosphatidylethanolamines and phosphatidylcholines. In stationary phase cultures, both white and opaque cells had slightly higher proportions of polar lipids. Major differences in the lipid composition between white and opaque cells involved the contents of free sterols and derivatives of sterols. White cells contained higher proportions of free sterols than opaque cells, while opaque cells contained more steryl glycosides and steryl esters (approximately 2·5 times higher). Comparison of the sterols of the white and opaque cells by UV, TLC and GLC showed that a qualitative as well as quantitative difference exists between the two phenotypes. Fatty acid analysis of white and opaque cells showed that C-16 and C-18 fatty acids are the most abundant in both phenotypes. White and opaque cells varied in their fatty acid composition. The former had higher proportions of palmitoleic (16:1) and stearic (18:0) but lower proportions of linoleic (18:2) fatty acids than opaque cells. Analysis of fatty acids of major lipid classes present in both forms showed that fatty acid pattern varied dramatically according to whether the class had been isolated from white or opaque cells. Our results suggest that the lipid composition (particularly sterol and polyunsaturated fatty acids) of the opaque phenotype resembles that of mycelial cultures. Opaque cells showed more resistance to amphotericin B, nystatin, 5-fluorocytosine (flucytosine) and miconazole nitrate than white cells." @default.
• W4300550988 created "2022-10-03" @default.
• W4300550988 creator A5003935045 @default.
• W4300550988 creator A5050023212 @default.
• W4300550988 creator A5089635085 @default.
• W4300550988 date "1990-01-01" @default.
• W4300550988 modified "2023-10-02" @default.
• W4300550988 title "Variation in lipid and sterol contents in<i>Candida albicans</i>white and opaque phenotypes" @default.
• W4300550988 cites W1505389209 @default.
• W4300550988 cites W1893930770 @default.
• W4300550988 cites W1968658612 @default.
• W4300550988 cites W1988312341 @default.
• W4300550988 cites W1989672570 @default.
• W4300550988 cites W2008832644 @default.
• W4300550988 cites W2022991426 @default.
• W4300550988 cites W2025378829 @default.
• W4300550988 cites W2028414840 @default.
• W4300550988 cites W2036456018 @default.
• W4300550988 cites W2051667899 @default.
• W4300550988 cites W2052917827 @default.
• W4300550988 cites W2113880496 @default.
• W4300550988 cites W2120232022 @default.
• W4300550988 cites W2158313582 @default.
• W4300550988 cites W2168526937 @default.
• W4300550988 cites W2171510356 @default.
• W4300550988 cites W2199677489 @default.
• W4300550988 cites W4213261779 @default.
• W4300550988 cites W4233537042 @default.
• W4300550988 doi "https://doi.org/10.1080/02681219080000151" @default.
• W4300550988 hasPublicationYear "1990" @default.
• W4300550988 type Work @default.
• W4300550988 citedByCount "28" @default.
• W4300550988 countsByYear W43005509882012 @default.
• W4300550988 countsByYear W43005509882016 @default.
• W4300550988 countsByYear W43005509882017 @default.
• W4300550988 countsByYear W43005509882020 @default.
• W4300550988 countsByYear W43005509882022 @default.
• W4300550988 crossrefType "journal-article" @default.
• W4300550988 hasAuthorship W4300550988A5003935045 @default.
• W4300550988 hasAuthorship W4300550988A5050023212 @default.
• W4300550988 hasAuthorship W4300550988A5089635085 @default.
• W4300550988 hasConcept C120665830 @default.
• W4300550988 hasConcept C121332964 @default.
• W4300550988 hasConcept C178790620 @default.
• W4300550988 hasConcept C185592680 @default.
• W4300550988 hasConcept C200514077 @default.
• W4300550988 hasConcept C2778163477 @default.
• W4300550988 hasConcept C2778718757 @default.
• W4300550988 hasConcept C2779516699 @default.
• W4300550988 hasConcept C543025807 @default.
• W4300550988 hasConcept C55493867 @default.
• W4300550988 hasConcept C60056205 @default.
• W4300550988 hasConcept C86803240 @default.
• W4300550988 hasConceptScore W4300550988C120665830 @default.
• W4300550988 hasConceptScore W4300550988C121332964 @default.
• W4300550988 hasConceptScore W4300550988C178790620 @default.
• W4300550988 hasConceptScore W4300550988C185592680 @default.
• W4300550988 hasConceptScore W4300550988C200514077 @default.
• W4300550988 hasConceptScore W4300550988C2778163477 @default.
• W4300550988 hasConceptScore W4300550988C2778718757 @default.
• W4300550988 hasConceptScore W4300550988C2779516699 @default.
• W4300550988 hasConceptScore W4300550988C543025807 @default.
• W4300550988 hasConceptScore W4300550988C55493867 @default.
• W4300550988 hasConceptScore W4300550988C60056205 @default.
• W4300550988 hasConceptScore W4300550988C86803240 @default.
• W4300550988 hasIssue "2" @default.
• W4300550988 hasLocation W43005509881 @default.
• W4300550988 hasOpenAccess W4300550988 @default.
• W4300550988 hasPrimaryLocation W43005509881 @default.
• W4300550988 hasRelatedWork W1965786512 @default.
• W4300550988 hasRelatedWork W1992728861 @default.
• W4300550988 hasRelatedWork W2000742042 @default.
• W4300550988 hasRelatedWork W2015112098 @default.
• W4300550988 hasRelatedWork W2027462942 @default.
• W4300550988 hasRelatedWork W203250823 @default.
• W4300550988 hasRelatedWork W2036923735 @default.
• W4300550988 hasRelatedWork W2069751187 @default.
• W4300550988 hasRelatedWork W2078578606 @default.
• W4300550988 hasRelatedWork W2101294930 @default.
• W4300550988 hasVolume "28" @default.
• W4300550988 isParatext "false" @default.
• W4300550988 isRetracted "false" @default.
• W4300550988 workType "article" @default.