Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300590927> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W4300590927 abstract "Recently, Hajirasouliha and Raphael (WABI 2014) proposed a model for deconvoluting mixed tumor samples measured from a collection of high-throughput sequencing reads. This is related to understanding tumor evolution and critical cancer mutations. In short, their formulation asks to split each row of a binary matrix so that the resulting matrix corresponds to a perfect phylogeny and has the minimum number of rows among all matrices with this property. In this paper we disprove several claims about this problem, including an NP-hardness proof of it. However, we show that the problem is indeed NP-hard, by providing a different proof. We also prove NP-completeness of a variant of this problem proposed in the same paper. On the positive side, we propose an efficient (though not necessarily optimal) heuristic algorithm based on coloring co-comparability graphs, and a polynomial time algorithm for solving the problem optimally on matrix instances in which no column is contained in both columns of a pair of conflicting columns. Implementations of these algorithms are freely available at https://github.com/alexandrutomescu/MixedPerfectPhylogeny" @default.
- W4300590927 created "2022-10-03" @default.
- W4300590927 creator A5002440751 @default.
- W4300590927 creator A5027970574 @default.
- W4300590927 creator A5039858919 @default.
- W4300590927 creator A5040690366 @default.
- W4300590927 creator A5063897224 @default.
- W4300590927 date "2015-06-25" @default.
- W4300590927 modified "2023-10-01" @default.
- W4300590927 title "Complexity and algorithms for finding a perfect phylogeny from mixed tumor samples" @default.
- W4300590927 doi "https://doi.org/10.48550/arxiv.1506.07675" @default.
- W4300590927 hasPublicationYear "2015" @default.
- W4300590927 type Work @default.
- W4300590927 citedByCount "0" @default.
- W4300590927 crossrefType "posted-content" @default.
- W4300590927 hasAuthorship W4300590927A5002440751 @default.
- W4300590927 hasAuthorship W4300590927A5027970574 @default.
- W4300590927 hasAuthorship W4300590927A5039858919 @default.
- W4300590927 hasAuthorship W4300590927A5040690366 @default.
- W4300590927 hasAuthorship W4300590927A5063897224 @default.
- W4300590927 hasBestOaLocation W43005909271 @default.
- W4300590927 hasConcept C106487976 @default.
- W4300590927 hasConcept C11413529 @default.
- W4300590927 hasConcept C114614502 @default.
- W4300590927 hasConcept C118615104 @default.
- W4300590927 hasConcept C126255220 @default.
- W4300590927 hasConcept C134306372 @default.
- W4300590927 hasConcept C159985019 @default.
- W4300590927 hasConcept C17231256 @default.
- W4300590927 hasConcept C173801870 @default.
- W4300590927 hasConcept C192562407 @default.
- W4300590927 hasConcept C197947376 @default.
- W4300590927 hasConcept C33923547 @default.
- W4300590927 hasConcept C41008148 @default.
- W4300590927 hasConcept C48372109 @default.
- W4300590927 hasConcept C94375191 @default.
- W4300590927 hasConceptScore W4300590927C106487976 @default.
- W4300590927 hasConceptScore W4300590927C11413529 @default.
- W4300590927 hasConceptScore W4300590927C114614502 @default.
- W4300590927 hasConceptScore W4300590927C118615104 @default.
- W4300590927 hasConceptScore W4300590927C126255220 @default.
- W4300590927 hasConceptScore W4300590927C134306372 @default.
- W4300590927 hasConceptScore W4300590927C159985019 @default.
- W4300590927 hasConceptScore W4300590927C17231256 @default.
- W4300590927 hasConceptScore W4300590927C173801870 @default.
- W4300590927 hasConceptScore W4300590927C192562407 @default.
- W4300590927 hasConceptScore W4300590927C197947376 @default.
- W4300590927 hasConceptScore W4300590927C33923547 @default.
- W4300590927 hasConceptScore W4300590927C41008148 @default.
- W4300590927 hasConceptScore W4300590927C48372109 @default.
- W4300590927 hasConceptScore W4300590927C94375191 @default.
- W4300590927 hasLocation W43005909271 @default.
- W4300590927 hasLocation W43005909272 @default.
- W4300590927 hasOpenAccess W4300590927 @default.
- W4300590927 hasPrimaryLocation W43005909271 @default.
- W4300590927 hasRelatedWork W1964518699 @default.
- W4300590927 hasRelatedWork W1970705056 @default.
- W4300590927 hasRelatedWork W1978042415 @default.
- W4300590927 hasRelatedWork W1979223578 @default.
- W4300590927 hasRelatedWork W2036204729 @default.
- W4300590927 hasRelatedWork W2246870267 @default.
- W4300590927 hasRelatedWork W2324155164 @default.
- W4300590927 hasRelatedWork W2359199758 @default.
- W4300590927 hasRelatedWork W2361310595 @default.
- W4300590927 hasRelatedWork W4245749626 @default.
- W4300590927 isParatext "false" @default.
- W4300590927 isRetracted "false" @default.
- W4300590927 workType "article" @default.