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- W4300660258 abstract "AIDS researchers are wondering if the pace of treatment improvements can be sustained. A panel of AIDS experts discusses resistance patterns, viral load testing, patient compliance, and treatment options. Although protease inhibitors are highly effective, drug resistance is a major concern and many patients fail on these drug regimens. When resistance develops to one protease inhibitor, it affects the body's response to other drugs of the same class. Overlapping resistance is further complicated by the difficulty of taking the drug cocktail as required since some patients cannot tolerate the treatment. Many clinicians advocate treating the disease aggressively and early; however, it may be wiser to defer treatment in patients who are unenthusiastic about the therapy or at low risk of disease progression. The question remains as to whether complete suppression of HIV will be possible with new treatments. Many patients do well and progress to having undetectable levels of HIV virus on a three-drug regimen; however, the result is unpredictable. Although there are eleven antiretroviral drugs available, the combination treatments are limited given the overlapping resistance patterns." @default.
- W4300660258 created "2022-10-03" @default.
- W4300660258 date "1997-10-01" @default.
- W4300660258 modified "2023-10-18" @default.
- W4300660258 title "Alarmed researchers push for more aggressive treatment and monitoring." @default.
- W4300660258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11364714" @default.
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