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- W4300687547 abstract "ABSTRACT We looked at the overlap between brain areas related to perception of physiologically and socially (non-physiological) needed stimuli and how they might regulate serotonin levels. First, we conducted separate ALE meta-analyses on published results pertaining to brain activation patterns when participants perceived food while hungry or water while thirsty, and social interactions while being excluded. This allowed us to identify common consistent brain activation patterns for physiological and social needed stimuli. We also looked at significant spatial association between the common network and serotonin receptor distribution. We found that regions within the mid-posterior insula, the anterior cingulate cortex and the caudate are at the intersection of physiological (hunger and thirst) and social (exclusion) aspects of ‘needing’. Furthermore, we found a significant positive spatial correlation between that common network and 5HT4 receptor among serotonin receptors. While this was the highest for serotonin receptors, it was not the highest of all receptors. Our study suggests there is a common brain pattern during the processing of physiologically and socially needed stimuli, and discusses their spatial association with serotonin receptors and its possible implication." @default.
- W4300687547 created "2022-10-04" @default.
- W4300687547 creator A5055374951 @default.
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- W4300687547 date "2022-10-03" @default.
- W4300687547 modified "2023-10-16" @default.
- W4300687547 title "Common brain areas for processing physiologically and socially ‘needed’ stimuli" @default.
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- W4300687547 doi "https://doi.org/10.1101/2022.09.30.510041" @default.
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