Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300687628> ?p ?o ?g. }
- W4300687628 endingPage "94" @default.
- W4300687628 startingPage "71" @default.
- W4300687628 abstract "Depression and anxiety are highly prevalent among individuals struggling with infertility. Thus, numerous psychological interventions have been adapted to infertility, with the aim of relieving distress as well as increasing pregnancy rates.This systematic review and meta-analysis aimed to identify all randomized controlled trials (RCTs) evaluating the effect of psychological interventions on infertility-related distress and pregnancy rates among individuals and/or couples with infertility and to analyse their overall effect. It also sought to examine potential treatment moderators, including intervention length, format and therapeutic approach.An electronic search of 11 databases, including MEDLINE, EMBASE, PsycINFO and Cochrane Central Register of Controlled Trials, was performed for studies published until January 2022. The inclusion criteria were RCTs conducted on humans and published in English. Psychological outcomes of interest included anxiety, depression, infertility-related distress, wellbeing and marital satisfaction. The Cochrane Risk of Bias tool was used to assess study quality, and the Grading of Recommendations Assessment, Development and Evaluation was used to assess the overall quality of the research evidence.There were 58 RCTs in total, including 54 which included psychological outcomes and 21 which assessed pregnancy rates. Studies originated from all regions of the world, but nearly half of the studies were from the Middle East. Although a beneficial effect on combined psychological outcomes was found (Hedge's g = 0.82, P < 0.0001), it was moderated by region (P < 0.00001) such that studies from the Middle East exhibited large effects (g = 1.40, P < 0.0001), while the effects were small among studies conducted elsewhere (g = 0.23, P < 0.0001). Statistically adjusting for study region in a meta-regression, neither intervention length, therapeutic approach, therapy format, nor participant gender (P > 0.05) moderated the effect of treatment. A beneficial treatment effect on pregnancy (RR (95% CI) = 1.25 (1.07-1.47), P = 0.005) was not moderated by region, treatment length, approach or format (P > 0.05). Largely due to the lack of high quality RCTs, the quality of the available evidence was rated as low to moderate.This is the first meta-analysis of RCTs testing the effect of psychological interventions on infertility-related distress and pregnancy rates. These findings suggest that in most regions of the world, psychological interventions are associated with small reductions in distress and modest effects on conception, suggesting the need for more effective interventions. These findings must be considered in light of the fact that the majority of the included RCTs were deemed to be at high risk of bias. Rigorously conducted trials are needed." @default.
- W4300687628 created "2022-10-04" @default.
- W4300687628 creator A5009905692 @default.
- W4300687628 creator A5038317304 @default.
- W4300687628 creator A5064887280 @default.
- W4300687628 creator A5073823223 @default.
- W4300687628 date "2022-10-03" @default.
- W4300687628 modified "2023-10-05" @default.
- W4300687628 title "Efficacy of psychological interventions for mental health and pregnancy rates among individuals with infertility: a systematic review and meta-analysis" @default.
- W4300687628 cites W1903329615 @default.
- W4300687628 cites W1909241615 @default.
- W4300687628 cites W1964680262 @default.
- W4300687628 cites W1970829383 @default.
- W4300687628 cites W1975219293 @default.
- W4300687628 cites W1980335974 @default.
- W4300687628 cites W1983574057 @default.
- W4300687628 cites W1985326609 @default.
- W4300687628 cites W1985938816 @default.
- W4300687628 cites W1986303419 @default.
- W4300687628 cites W2004049904 @default.
- W4300687628 cites W2010199691 @default.
- W4300687628 cites W2016272166 @default.
- W4300687628 cites W2046841265 @default.
- W4300687628 cites W2048717808 @default.
- W4300687628 cites W2052241354 @default.
- W4300687628 cites W2052344142 @default.
- W4300687628 cites W2055859834 @default.
- W4300687628 cites W2059147557 @default.
- W4300687628 cites W2059527510 @default.
- W4300687628 cites W2059814460 @default.
- W4300687628 cites W2060775552 @default.
- W4300687628 cites W2065093053 @default.
- W4300687628 cites W2073199780 @default.
- W4300687628 cites W2075912479 @default.
- W4300687628 cites W2085001923 @default.
- W4300687628 cites W2100438861 @default.
- W4300687628 cites W2103859384 @default.
- W4300687628 cites W2110001630 @default.
- W4300687628 cites W2117200377 @default.
- W4300687628 cites W2119479230 @default.
- W4300687628 cites W2120737222 @default.
- W4300687628 cites W2125435699 @default.
- W4300687628 cites W2126930838 @default.
- W4300687628 cites W2127679870 @default.
- W4300687628 cites W2127996501 @default.
- W4300687628 cites W2131785062 @default.
- W4300687628 cites W2132989097 @default.
- W4300687628 cites W2147830561 @default.
- W4300687628 cites W2148326029 @default.
- W4300687628 cites W2152781775 @default.
- W4300687628 cites W2153403283 @default.
- W4300687628 cites W2155873132 @default.
- W4300687628 cites W2156698186 @default.
- W4300687628 cites W2159926515 @default.
- W4300687628 cites W2162459238 @default.
- W4300687628 cites W2165010366 @default.
- W4300687628 cites W2168389362 @default.
- W4300687628 cites W2268213157 @default.
- W4300687628 cites W2300249434 @default.
- W4300687628 cites W2305001145 @default.
- W4300687628 cites W2413223681 @default.
- W4300687628 cites W2515954161 @default.
- W4300687628 cites W2566781465 @default.
- W4300687628 cites W2596084277 @default.
- W4300687628 cites W2809870503 @default.
- W4300687628 cites W2891639777 @default.
- W4300687628 cites W2895791894 @default.
- W4300687628 cites W2921088020 @default.
- W4300687628 cites W2930547731 @default.
- W4300687628 cites W2938284809 @default.
- W4300687628 cites W2946777304 @default.
- W4300687628 cites W2957317699 @default.
- W4300687628 cites W2976589440 @default.
- W4300687628 cites W2983503530 @default.
- W4300687628 cites W2996880788 @default.
- W4300687628 cites W3005580810 @default.
- W4300687628 cites W3010708957 @default.
- W4300687628 cites W3017233882 @default.
- W4300687628 cites W3042339300 @default.
- W4300687628 cites W3088905138 @default.
- W4300687628 cites W3111802305 @default.
- W4300687628 cites W3121097328 @default.
- W4300687628 cites W3128888551 @default.
- W4300687628 cites W3133125451 @default.
- W4300687628 cites W4200204193 @default.
- W4300687628 cites W4245760443 @default.
- W4300687628 cites W4253046392 @default.
- W4300687628 cites W4294215472 @default.
- W4300687628 doi "https://doi.org/10.1093/humupd/dmac034" @default.
- W4300687628 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36191078" @default.
- W4300687628 hasPublicationYear "2022" @default.
- W4300687628 type Work @default.
- W4300687628 citedByCount "3" @default.
- W4300687628 countsByYear W43006876282023 @default.
- W4300687628 crossrefType "journal-article" @default.
- W4300687628 hasAuthorship W4300687628A5009905692 @default.
- W4300687628 hasAuthorship W4300687628A5038317304 @default.
- W4300687628 hasAuthorship W4300687628A5064887280 @default.