FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300690595> ?p ?o ?g. }

• W4300690595 endingPage "404" @default.
• W4300690595 startingPage "397" @default.
• W4300690595 abstract "Long-term follow-up has been recommended for patients with pheochromocytoma or paraganglioma (PPGL) due to potential for recurrent disease. However, the need to follow patients with sporadic PPGL has recently become controversial.To investigate the prevalence of recurrence among patients with sporadic compared with hereditary PPGL and to identify predictors of recurrence for sporadic disease.This multicenter study included retrospective data from 1127 patients with PPGL. In addition to sex and age at primary tumor diagnosis, clinical information included location, size, and catecholamine phenotype of primary tumors, genetic test results, and subsequent development of recurrent and/or metastatic disease. Patients with sporadic PPGL were defined as those with negative genetic test results.Prevalence of recurrence among patients with sporadic PPGL (14.7%) was lower (P < 0.001) than for patients with pathogenic variants that activate pseudohypoxia pathways (47.5%), but similar to those with variants that activate kinase pathways (14.9%). Among patients with sporadic recurrent PPGL, 29.1% and 17.7% were respectively diagnosed at least 10 and 15 years after first diagnosis. Multivariable regression analysis showed that a noradrenergic/dopaminergic phenotype (HR 2.73; 95% CI, 1.553-4.802; P < 0.001), larger size (HR 1.82; 95% CI, 1.113-2.962; P = 0.017) and extra-adrenal location (HR 1.79; 95% CI, 1.002-3.187; P = 0.049) of primary tumors were independent predictors of recurrence in sporadic PPGL.Patients with sporadic PPGL require long-term follow-up, as supported by the 14.7% prevalence of recurrent disease, including recurrences at more than 10 years after first diagnosis. The nature of follow-up could be individualized according to tumor size, location, and biochemical phenotype." @default.
• W4300690595 created "2022-10-04" @default.
• W4300690595 creator A5002954106 @default.
• W4300690595 creator A5005313542 @default.
• W4300690595 creator A5005679973 @default.
• W4300690595 creator A5007794291 @default.
• W4300690595 creator A5029003117 @default.
• W4300690595 creator A5038915725 @default.
• W4300690595 creator A5041910578 @default.
• W4300690595 creator A5046768397 @default.
• W4300690595 creator A5048446979 @default.
• W4300690595 creator A5051607812 @default.
• W4300690595 creator A5064052833 @default.
• W4300690595 creator A5064807965 @default.
• W4300690595 creator A5068457694 @default.
• W4300690595 creator A5069344737 @default.
• W4300690595 creator A5079200195 @default.
• W4300690595 creator A5081843282 @default.
• W4300690595 creator A5090455680 @default.
• W4300690595 date "2022-10-03" @default.
• W4300690595 modified "2023-09-27" @default.
• W4300690595 title "Recurrent Disease in Patients With Sporadic Pheochromocytoma and Paraganglioma" @default.
• W4300690595 cites W1977593894 @default.
• W4300690595 cites W1977775131 @default.
• W4300690595 cites W1988823135 @default.
• W4300690595 cites W2011457427 @default.
• W4300690595 cites W2032516847 @default.
• W4300690595 cites W2052953554 @default.
• W4300690595 cites W2057275256 @default.
• W4300690595 cites W2088868003 @default.
• W4300690595 cites W2096986655 @default.
• W4300690595 cites W2099532184 @default.
• W4300690595 cites W2101065691 @default.
• W4300690595 cites W2124658920 @default.
• W4300690595 cites W2168560579 @default.
• W4300690595 cites W2184486774 @default.
• W4300690595 cites W2252310090 @default.
• W4300690595 cites W2333098768 @default.
• W4300690595 cites W2336340905 @default.
• W4300690595 cites W2561885490 @default.
• W4300690595 cites W2585589460 @default.
• W4300690595 cites W2611789810 @default.
• W4300690595 cites W2626337139 @default.
• W4300690595 cites W2924758046 @default.
• W4300690595 cites W2978516717 @default.
• W4300690595 cites W3030481513 @default.
• W4300690595 cites W3047453848 @default.
• W4300690595 cites W3086182333 @default.
• W4300690595 cites W3090931313 @default.
• W4300690595 cites W3095367768 @default.
• W4300690595 cites W3193508421 @default.
• W4300690595 cites W3199508038 @default.
• W4300690595 cites W3199969270 @default.
• W4300690595 cites W3213095573 @default.
• W4300690595 cites W4220716887 @default.
• W4300690595 cites W4225164047 @default.
• W4300690595 cites W4250364331 @default.
• W4300690595 cites W4282914913 @default.
• W4300690595 cites W4300690595 @default.
• W4300690595 cites W43616094 @default.
• W4300690595 cites W81642142 @default.
• W4300690595 doi "https://doi.org/10.1210/clinem/dgac563" @default.
• W4300690595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36190922" @default.
• W4300690595 hasPublicationYear "2022" @default.
• W4300690595 type Work @default.
• W4300690595 citedByCount "6" @default.
• W4300690595 countsByYear W43006905952022 @default.
• W4300690595 countsByYear W43006905952023 @default.
• W4300690595 crossrefType "journal-article" @default.
• W4300690595 hasAuthorship W4300690595A5002954106 @default.
• W4300690595 hasAuthorship W4300690595A5005313542 @default.
• W4300690595 hasAuthorship W4300690595A5005679973 @default.
• W4300690595 hasAuthorship W4300690595A5007794291 @default.
• W4300690595 hasAuthorship W4300690595A5029003117 @default.
• W4300690595 hasAuthorship W4300690595A5038915725 @default.
• W4300690595 hasAuthorship W4300690595A5041910578 @default.
• W4300690595 hasAuthorship W4300690595A5046768397 @default.
• W4300690595 hasAuthorship W4300690595A5048446979 @default.
• W4300690595 hasAuthorship W4300690595A5051607812 @default.
• W4300690595 hasAuthorship W4300690595A5064052833 @default.
• W4300690595 hasAuthorship W4300690595A5064807965 @default.
• W4300690595 hasAuthorship W4300690595A5068457694 @default.
• W4300690595 hasAuthorship W4300690595A5069344737 @default.
• W4300690595 hasAuthorship W4300690595A5079200195 @default.
• W4300690595 hasAuthorship W4300690595A5081843282 @default.
• W4300690595 hasAuthorship W4300690595A5090455680 @default.
• W4300690595 hasBestOaLocation W43006905952 @default.
• W4300690595 hasConcept C126322002 @default.
• W4300690595 hasConcept C134018914 @default.
• W4300690595 hasConcept C142724271 @default.
• W4300690595 hasConcept C143998085 @default.
• W4300690595 hasConcept C167135981 @default.
• W4300690595 hasConcept C2776734335 @default.
• W4300690595 hasConcept C2779134260 @default.
• W4300690595 hasConcept C2779512018 @default.
• W4300690595 hasConcept C2780673598 @default.
• W4300690595 hasConcept C71924100 @default.
• W4300690595 hasConcept C90924648 @default.

• next