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- W4300693638 abstract "We describe the clinical and biochemical characteristics of alcoholinduced pseudo-Cushing's syndrome in two patients with signs and symptoms of Cushing's syndrome and slight disturbances in liver function. An insufficient suppression of plasma cortisol to the overnight administration of 1 mg of dexamethasone was accompanied by an absent diurnal rhythm of plasma cortisol and an increased cortisol secretion rate. The plasma cortisol levels at 8 AM normalized during hospital admission (ie, alcohol withdrawal) at the same rate or parallel with the serum 7-glutamyl transferase concentration. A normal increase of plasma cortisol, adrenocorticotropic hormone, and growth hormone in response to an insulin-induced hypoglycemia was not compatible with the diagnosis Cushing's syndrome. However, the result of a differential diagnostic test with metyrapone was compatible with the presence of Cushing's disease. An erroneous diagnosis of Cushing's disease can be easily made in patients with alcohol-induced pseudo-Cushing's syndrome. (<i>JAMA</i>242:1640-1643, 1979)" @default.
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- W4300693638 date "1979-10-12" @default.
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- W4300693638 title "Hormone Secretion in Alcohol-Induced Pseudo-Cushing's Syndrome" @default.
- W4300693638 doi "https://doi.org/10.1001/jama.1979.03300150038024" @default.
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