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- W4300725180 abstract "Sixty healthy mothers undergoing elective cesarean section received at random either midazolam 0.2 mg/kg or thiopental 3.5 mg/kg with succinylcholine 1 mg/kg for rapid sequence intravenous anesthetic induction. Maintenance of anesthesia was identical in all patients: 50:50 N2O in oxygen, halothane 0.5% and pancuronium 0.05 mglkg. Hemodynamic responses were similar, as were the biochemical status of mothers and infants, and maternal to fetal blood gaslacid base gradients. Correlation between maternal arterial and fetal (umbilical venous/arterial) pH, PCO2 and base excess values were statistically better with midazolam. However, 1-min Apgar minus color (A-C) scores < 5/8 (representing “severe” neonatal depression) were recorded in five infants after midazolam, three of whom required tracheal intubation, and one whose mother was given thiopental. This difference reached statistical significance (P < 0.05). It is concluded that midazolam is less suitable than thiopental for anesthetic induction in patients undergoing cesarean section." @default.
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- W4300725180 date "1987-11-01" @default.
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- W4300725180 title "Comparison of Midazolam and Thiopental for Rapid Sequence Anesthetic Induction for Elective Cesarean Section" @default.
- W4300725180 doi "https://doi.org/10.1213/00000539-198711000-00016" @default.
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