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• W4300773189 abstract "Background. Although a lot of research work has been done on the etiology and pathogenesis of hypertensive disorder complicating pregnancy at home and abroad, the exact etiology and pathogenesis of the disease are still uncertain so far. Aims. Systematic review of meta-analysis of differences in serum lipid levels between pregnant women with hypertensive disease complicated with pregnancy and nonhypertensive disease complicated with pregnancy. Materials and Methods. PubMed, Medline, Embase, Science Citation Index (SCI), Cochrane, Springer, CNKI, Wanfang, VIP, and other databases were used to retrieve published literature and evaluate the included literature according to the quality evaluation method of medical literature introduced by the Cochrane Collaboration. A systematic review of the included studies was performed by meta-analysis. Results. We included 9 articles that documented total bile acids and D-dimers. In the heterogeneity test ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M1> <mi>P</mi> <mo><</mo> <mn>0.05</mn> </math> , <math xmlns=http://www.w3.org/1998/Math/MathML id=M2> <msup> <mrow> <mi>I</mi> </mrow> <mrow> <mn>2</mn> </mrow> </msup> <mo>=</mo> <mn>100</mn> <mi>%</mi> <mo>></mo> <mn>50</mn> <mi>%</mi> </math> ), it was considered that the study was heterogeneous, so sensitivity analysis was used, the fixed-effect model was replaced, and the results were not significantly different after each item was excluded. Reliably, the difference was statistically significant ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M3> <mi>Z</mi> <mo>=</mo> <mn>7.32</mn> </math> , <math xmlns=http://www.w3.org/1998/Math/MathML id=M4> <mi>P</mi> <mo><</mo> <mn>0.001</mn> </math> ). In the TG metaheterogeneity test, <math xmlns=http://www.w3.org/1998/Math/MathML id=M5> <mi>P</mi> <mo><</mo> <mn>0.05</mn> </math> , <math xmlns=http://www.w3.org/1998/Math/MathML id=M6> <msup> <mrow> <mi>I</mi> </mrow> <mrow> <mn>2</mn> </mrow> </msup> <mo>=</mo> <mn>99</mn> <mi>%</mi> <mo>></mo> <mn>50</mn> <mi>%</mi> </math> , to explore the source of heterogeneity and conduct sensitivity analysis and switch to fixed-effect model, the difference was not statistically significant ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M7> <mi>P</mi> <mo>></mo> <mn>0.05</mn> </math> ). There was no significant difference in TC between hypertensive disorder complicating pregnancy and nonhypertensive disorder complicating pregnancy ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M8> <mi>P</mi> <mo>></mo> <mn>0.001</mn> </math> ). Conclusion. D-dimer, total bile acids, and glycopyrrolate were highly expressed in the sera of pregnant women with hypertensive disorder complicating pregnancy dyslipidemia." @default.
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• W4300773189 date "2022-10-03" @default.
• W4300773189 modified "2023-10-14" @default.
• W4300773189 title "A Meta-Analysis of the Differences in Serum Lipid Levels between Pregnant Women with Hypertensive Disorder Complicating Pregnancy and Nonhypertensive Disorder Complicating Pregnancy" @default.
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• W4300773189 doi "https://doi.org/10.1155/2022/8974924" @default.
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