Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300781694> ?p ?o ?g. }
- W4300781694 endingPage "1245" @default.
- W4300781694 startingPage "1241" @default.
- W4300781694 abstract "The effect of acute and chronic ethanol treatment on the activity of tissue transglutaminase (a calcium-dependent enzyme that catalyzes the covalent association between proteins, as well as proteins and polyamines) was studied in homogenate and in the cytosolic fraction of rat brain (telencephalon and diencephalon). A single dose of ethanol (5 g/kg of body weight, by gastric intubation) caused a 2-fold increase in enzyme activity at 6 hr after the ethanol dose, with a return toward the basal values at 24 hr. In vitro experiments with ethanol or acetaldehyde showed that the increase in transglutaminase activity was due to ethanol per se and not to its metabolism. The enzyme stimulation was correlated with a decrease in the levels of the polyamine spermine, a physiological substrate for the enzyme. Similar results were also found in the brain from rats fed on an ethanol diet for 4 months. The enhancement in tissue transglutaminase activity may thus lead to a decline in spermine, a polyamine known to have important protective functions in the cell." @default.
- W4300781694 created "2022-10-04" @default.
- W4300781694 creator A5030409570 @default.
- W4300781694 creator A5036070188 @default.
- W4300781694 creator A5050267989 @default.
- W4300781694 creator A5057643433 @default.
- W4300781694 date "1997-10-01" @default.
- W4300781694 modified "2023-10-17" @default.
- W4300781694 title "Transglutaminase Activity in Rat Brain after Ethanol Exposure" @default.
- W4300781694 cites W1454003142 @default.
- W4300781694 cites W1486999320 @default.
- W4300781694 cites W1543008345 @default.
- W4300781694 cites W1775749144 @default.
- W4300781694 cites W1892184508 @default.
- W4300781694 cites W1963849454 @default.
- W4300781694 cites W1971735319 @default.
- W4300781694 cites W1975565192 @default.
- W4300781694 cites W1975751663 @default.
- W4300781694 cites W1978991174 @default.
- W4300781694 cites W1986928159 @default.
- W4300781694 cites W1993484927 @default.
- W4300781694 cites W1999560094 @default.
- W4300781694 cites W2001831298 @default.
- W4300781694 cites W2003190846 @default.
- W4300781694 cites W2008478633 @default.
- W4300781694 cites W2008489714 @default.
- W4300781694 cites W2014319334 @default.
- W4300781694 cites W2020196912 @default.
- W4300781694 cites W2024775862 @default.
- W4300781694 cites W2026744575 @default.
- W4300781694 cites W2029895368 @default.
- W4300781694 cites W2037752373 @default.
- W4300781694 cites W2038391384 @default.
- W4300781694 cites W2048107324 @default.
- W4300781694 cites W2049211009 @default.
- W4300781694 cites W2056118948 @default.
- W4300781694 cites W2058163213 @default.
- W4300781694 cites W2067335670 @default.
- W4300781694 cites W2068092742 @default.
- W4300781694 cites W2069172577 @default.
- W4300781694 cites W2079436545 @default.
- W4300781694 cites W2123831833 @default.
- W4300781694 cites W2126442538 @default.
- W4300781694 cites W2140224540 @default.
- W4300781694 cites W2411898170 @default.
- W4300781694 cites W4240943354 @default.
- W4300781694 doi "https://doi.org/10.1111/j.1530-0277.1997.tb04444.x" @default.
- W4300781694 hasPublicationYear "1997" @default.
- W4300781694 type Work @default.
- W4300781694 citedByCount "4" @default.
- W4300781694 countsByYear W43007816942012 @default.
- W4300781694 crossrefType "journal-article" @default.
- W4300781694 hasAuthorship W4300781694A5030409570 @default.
- W4300781694 hasAuthorship W4300781694A5036070188 @default.
- W4300781694 hasAuthorship W4300781694A5050267989 @default.
- W4300781694 hasAuthorship W4300781694A5057643433 @default.
- W4300781694 hasConcept C126322002 @default.
- W4300781694 hasConcept C134018914 @default.
- W4300781694 hasConcept C178498320 @default.
- W4300781694 hasConcept C181199279 @default.
- W4300781694 hasConcept C185592680 @default.
- W4300781694 hasConcept C2776109719 @default.
- W4300781694 hasConcept C2777595113 @default.
- W4300781694 hasConcept C2780115381 @default.
- W4300781694 hasConcept C2780161600 @default.
- W4300781694 hasConcept C2781159505 @default.
- W4300781694 hasConcept C28212737 @default.
- W4300781694 hasConcept C55493867 @default.
- W4300781694 hasConcept C71924100 @default.
- W4300781694 hasConcept C86803240 @default.
- W4300781694 hasConceptScore W4300781694C126322002 @default.
- W4300781694 hasConceptScore W4300781694C134018914 @default.
- W4300781694 hasConceptScore W4300781694C178498320 @default.
- W4300781694 hasConceptScore W4300781694C181199279 @default.
- W4300781694 hasConceptScore W4300781694C185592680 @default.
- W4300781694 hasConceptScore W4300781694C2776109719 @default.
- W4300781694 hasConceptScore W4300781694C2777595113 @default.
- W4300781694 hasConceptScore W4300781694C2780115381 @default.
- W4300781694 hasConceptScore W4300781694C2780161600 @default.
- W4300781694 hasConceptScore W4300781694C2781159505 @default.
- W4300781694 hasConceptScore W4300781694C28212737 @default.
- W4300781694 hasConceptScore W4300781694C55493867 @default.
- W4300781694 hasConceptScore W4300781694C71924100 @default.
- W4300781694 hasConceptScore W4300781694C86803240 @default.
- W4300781694 hasIssue "7" @default.
- W4300781694 hasLocation W43007816941 @default.
- W4300781694 hasOpenAccess W4300781694 @default.
- W4300781694 hasPrimaryLocation W43007816941 @default.
- W4300781694 hasRelatedWork W1966547107 @default.
- W4300781694 hasRelatedWork W1968714063 @default.
- W4300781694 hasRelatedWork W1992881709 @default.
- W4300781694 hasRelatedWork W2036727846 @default.
- W4300781694 hasRelatedWork W2055736750 @default.
- W4300781694 hasRelatedWork W2069172577 @default.
- W4300781694 hasRelatedWork W2143734654 @default.
- W4300781694 hasRelatedWork W2345067921 @default.
- W4300781694 hasRelatedWork W2530991042 @default.
- W4300781694 hasRelatedWork W4256255209 @default.