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- W4300818905 abstract "Dendrobium nobile (Lindl.) have long been used as herbal tea and a traditional herbal medicine to treat Alzheimer’s disease (AD). In the current study, nineteen compounds ( 1–19 ), including two new vitamin E homologues ( 1–2 ), one new sesquiterpene ( 6 ), and two new dendrobines ( 7 , 8 ), were isolated and identified from stems of Dendrobium nobile . Their structures were elucidated on the basis of NMR, 13 C NMR calculation, and DP4 + probability analyses. The absolute configurations of new compounds were determined by electronic circular dichroism (ECD) data analysis. Antioxidant, anti-inflammatory, and cytotoxic activities of isolated compounds were evaluated. Among them, compound 2 demonstrated significant antioxidant activity compared with ascorbic acid (VC), while compounds 2 and 4 also exhibited an equal effect to positive control cisplatin. This study on the biological activity of the new vitamin E homologues from Dendrobium nobile may indicate its potential application in the pharmaceutical and food industries." @default.
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- W4300818905 date "2022-10-04" @default.
- W4300818905 modified "2023-10-16" @default.
- W4300818905 title "Antioxidant and anti-inflammatory activity of constituents isolated from Dendrobium nobile (Lindl.)" @default.
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- W4300818905 doi "https://doi.org/10.3389/fchem.2022.988459" @default.
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