Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300836701> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4300836701 endingPage "7" @default.
- W4300836701 startingPage "1555" @default.
- W4300836701 abstract "In children with corticosteroid-responsive nephrotic syndrome who are dependent on high-dose prednisolone, alkylating therapy often fails to maintain a remission, and long-term immunosuppression may be hazardous. An alternative approach to treatment is to use an immunostimulant such as levamisole. 61 children with frequently relapsing corticosteroid sensitive and dependent nephrotic syndrome were randomly allocated to receive levamisole, 2.5 mg/kg on alternate days (31 patients) or placebo (30 patients) for a maximum of 112 days. After entry to the trial, prednisolone was progressively reduced and was stopped by 56 days. The two groups were well matched for age and sex distribution, indices of corticosteroid toxicity, and previous alkylating therapy. 14 patients in the levamisole group and 4 in the placebo group remained in remission at 112 days (log rank analysis p less than 0.01). No significant adverse events were recorded. Levamisole is effective in maintaining a steroid-free remission in this condition and has few side-effects." @default.
- W4300836701 created "2022-10-04" @default.
- W4300836701 date "1991-06-29" @default.
- W4300836701 modified "2023-09-29" @default.
- W4300836701 title "Levamisole for corticosteroid-dependent nephrotic syndrome in childhood. British Association for Paediatric Nephrology." @default.
- W4300836701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1675705" @default.
- W4300836701 hasPublicationYear "1991" @default.
- W4300836701 type Work @default.
- W4300836701 citedByCount "26" @default.
- W4300836701 countsByYear W43008367012015 @default.
- W4300836701 countsByYear W43008367012016 @default.
- W4300836701 countsByYear W43008367012018 @default.
- W4300836701 countsByYear W43008367012019 @default.
- W4300836701 countsByYear W43008367012020 @default.
- W4300836701 countsByYear W43008367012021 @default.
- W4300836701 countsByYear W43008367012023 @default.
- W4300836701 crossrefType "journal-article" @default.
- W4300836701 hasConcept C126322002 @default.
- W4300836701 hasConcept C142724271 @default.
- W4300836701 hasConcept C204787440 @default.
- W4300836701 hasConcept C27081682 @default.
- W4300836701 hasConcept C2776715498 @default.
- W4300836701 hasConcept C2776804153 @default.
- W4300836701 hasConcept C2778930706 @default.
- W4300836701 hasConcept C2780252810 @default.
- W4300836701 hasConcept C2781325985 @default.
- W4300836701 hasConcept C54847362 @default.
- W4300836701 hasConcept C71924100 @default.
- W4300836701 hasConcept C90924648 @default.
- W4300836701 hasConceptScore W4300836701C126322002 @default.
- W4300836701 hasConceptScore W4300836701C142724271 @default.
- W4300836701 hasConceptScore W4300836701C204787440 @default.
- W4300836701 hasConceptScore W4300836701C27081682 @default.
- W4300836701 hasConceptScore W4300836701C2776715498 @default.
- W4300836701 hasConceptScore W4300836701C2776804153 @default.
- W4300836701 hasConceptScore W4300836701C2778930706 @default.
- W4300836701 hasConceptScore W4300836701C2780252810 @default.
- W4300836701 hasConceptScore W4300836701C2781325985 @default.
- W4300836701 hasConceptScore W4300836701C54847362 @default.
- W4300836701 hasConceptScore W4300836701C71924100 @default.
- W4300836701 hasConceptScore W4300836701C90924648 @default.
- W4300836701 hasIssue "8757" @default.
- W4300836701 hasLocation W43008367011 @default.
- W4300836701 hasOpenAccess W4300836701 @default.
- W4300836701 hasPrimaryLocation W43008367011 @default.
- W4300836701 hasRelatedWork W143946301 @default.
- W4300836701 hasRelatedWork W1563965925 @default.
- W4300836701 hasRelatedWork W2017098202 @default.
- W4300836701 hasRelatedWork W2031954310 @default.
- W4300836701 hasRelatedWork W2062481152 @default.
- W4300836701 hasRelatedWork W2066185585 @default.
- W4300836701 hasRelatedWork W2416765620 @default.
- W4300836701 hasRelatedWork W2734949999 @default.
- W4300836701 hasRelatedWork W3153412378 @default.
- W4300836701 hasRelatedWork W4251694231 @default.
- W4300836701 hasVolume "337" @default.
- W4300836701 isParatext "false" @default.
- W4300836701 isRetracted "false" @default.
- W4300836701 workType "article" @default.