Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300851943> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4300851943 endingPage "282" @default.
- W4300851943 startingPage "269" @default.
- W4300851943 abstract "The morphology of postnatal human lung development and growth has been investigated by light and by scanning and transmission electron microscopy in seven children dying from non-respiratory causes and aged between 26 days and 64 months. The findings are compared with those of adult human lungs and are discussed in relation to the postnatal lung development in other species, particularly rodents. Within the first 112 postnatal years lung parenchyma undergoes a substantial structural remodeling due to bulk alveolar formation and to the restructuring of septal morphology. At one month alveolar formation appears to be well under way: The human lung is comparable then to a rat lung aged one week. In the parenchyma, numerous short and blunt tissue ridges, so-called secondary septa, subdivide the peripheral airspaces into an increasing number of still very shallow alveoli. the parenchymal septa present during and after alveolization are immature: they contain a double capillary network with a central, highly cellular sheet of connective tissue. The septal maturation sets in a few months after birth and consists of a reduction in the interstitial tissue mass and a complex process of capillary remodeling. Both alveolization and parenchymal maturation progress rapidly: by 6 months the lung has taken a big step towards maturity. By 112 years most septa show the adult structure where a single capillary network interwoven with connective tissue strands stabilizes the interalveolar wall. After the septal restructuring, lung development is considered complete, and the lung enters a period of normal growth that lasts until adulthood. From our observations we conclude that postnatal human lung development is made of two overlapping stages: (a) the alveolar stage, which starts in late fetal life and lasts to about 1–112 years, and (b) a stage of microvascular maturation, thought to extend from the first months after birth to the age of 2–3 years." @default.
- W4300851943 created "2022-10-04" @default.
- W4300851943 creator A5022272695 @default.
- W4300851943 creator A5073452855 @default.
- W4300851943 date "1987-03-01" @default.
- W4300851943 modified "2023-10-18" @default.
- W4300851943 title "The postnatal development and growth of the human lung. II. Morphology" @default.
- W4300851943 cites W2011050399 @default.
- W4300851943 cites W2011408698 @default.
- W4300851943 cites W2011687479 @default.
- W4300851943 cites W2012279077 @default.
- W4300851943 cites W2015366946 @default.
- W4300851943 cites W2030135763 @default.
- W4300851943 cites W2039524106 @default.
- W4300851943 cites W2054637037 @default.
- W4300851943 cites W2057048199 @default.
- W4300851943 cites W2065003921 @default.
- W4300851943 cites W2082495239 @default.
- W4300851943 cites W2085165496 @default.
- W4300851943 cites W2091791887 @default.
- W4300851943 cites W2103668562 @default.
- W4300851943 cites W2108943436 @default.
- W4300851943 cites W2209701832 @default.
- W4300851943 cites W4230234871 @default.
- W4300851943 cites W4231268702 @default.
- W4300851943 doi "https://doi.org/10.1016/0034-5687(87)90058-2" @default.
- W4300851943 hasPublicationYear "1987" @default.
- W4300851943 type Work @default.
- W4300851943 citedByCount "173" @default.
- W4300851943 countsByYear W43008519432012 @default.
- W4300851943 countsByYear W43008519432013 @default.
- W4300851943 countsByYear W43008519432014 @default.
- W4300851943 countsByYear W43008519432015 @default.
- W4300851943 countsByYear W43008519432016 @default.
- W4300851943 countsByYear W43008519432017 @default.
- W4300851943 countsByYear W43008519432018 @default.
- W4300851943 countsByYear W43008519432019 @default.
- W4300851943 countsByYear W43008519432020 @default.
- W4300851943 countsByYear W43008519432021 @default.
- W4300851943 countsByYear W43008519432022 @default.
- W4300851943 countsByYear W43008519432023 @default.
- W4300851943 crossrefType "journal-article" @default.
- W4300851943 hasAuthorship W4300851943A5022272695 @default.
- W4300851943 hasAuthorship W4300851943A5073452855 @default.
- W4300851943 hasConcept C105702510 @default.
- W4300851943 hasConcept C126322002 @default.
- W4300851943 hasConcept C142724271 @default.
- W4300851943 hasConcept C196822366 @default.
- W4300851943 hasConcept C2777714996 @default.
- W4300851943 hasConcept C518705261 @default.
- W4300851943 hasConcept C534529494 @default.
- W4300851943 hasConcept C71924100 @default.
- W4300851943 hasConcept C86803240 @default.
- W4300851943 hasConceptScore W4300851943C105702510 @default.
- W4300851943 hasConceptScore W4300851943C126322002 @default.
- W4300851943 hasConceptScore W4300851943C142724271 @default.
- W4300851943 hasConceptScore W4300851943C196822366 @default.
- W4300851943 hasConceptScore W4300851943C2777714996 @default.
- W4300851943 hasConceptScore W4300851943C518705261 @default.
- W4300851943 hasConceptScore W4300851943C534529494 @default.
- W4300851943 hasConceptScore W4300851943C71924100 @default.
- W4300851943 hasConceptScore W4300851943C86803240 @default.
- W4300851943 hasIssue "3" @default.
- W4300851943 hasLocation W43008519431 @default.
- W4300851943 hasOpenAccess W4300851943 @default.
- W4300851943 hasPrimaryLocation W43008519431 @default.
- W4300851943 hasRelatedWork W1972477889 @default.
- W4300851943 hasRelatedWork W1992581245 @default.
- W4300851943 hasRelatedWork W1998429617 @default.
- W4300851943 hasRelatedWork W2128541281 @default.
- W4300851943 hasRelatedWork W2281741346 @default.
- W4300851943 hasRelatedWork W2395256833 @default.
- W4300851943 hasRelatedWork W2417903212 @default.
- W4300851943 hasRelatedWork W2463748233 @default.
- W4300851943 hasRelatedWork W2617262006 @default.
- W4300851943 hasRelatedWork W4248756257 @default.
- W4300851943 hasVolume "67" @default.
- W4300851943 isParatext "false" @default.
- W4300851943 isRetracted "false" @default.
- W4300851943 workType "article" @default.