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- W4300887313 abstract "Lymphocytotoxic or thrombocytolytic antibodies were detected in 11 of 25 thrombocytopenic patients receiving repeated platelet transfusions. Platelet survival times were reduced in these patients (half-life [T/2], 32 hours) as compared to patients without antibody (T/2, 51 hours,<i>P</i><.05). In one woman with acute myeloblastic leukemia and a potent platelet antibody, combination chemotherapy resulted in a profound decrease in circulating γ globulin and concurrent disappearance of the cytotoxic antibody. The survival of transfused platelets in this patient was dramatically improved, and bleeding was controlled. (<i>JAMA</i>236:1044-1046, 1976)" @default.
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- W4300887313 date "1976-08-30" @default.
- W4300887313 modified "2023-10-17" @default.
- W4300887313 title "Cytotoxic Antibody Complicating Platelet Support in Acute Leukemia" @default.
- W4300887313 doi "https://doi.org/10.1001/jama.1976.03270100044027" @default.
- W4300887313 hasPublicationYear "1976" @default.
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