Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300892004> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W4300892004 endingPage "39" @default.
- W4300892004 startingPage "39" @default.
- W4300892004 abstract "Patients with malignant lymphoproliferative diseases, ie, chronic lymphocytic leukemia and lymphoma, were found to have higher porphobilinogen deaminase (PBGD) activity in their peripheral lymphocytes than normal control subjects, patients with other malignant neoplasms, and patients with various infectious diseases. The specificity and sensitivity of the test were 99% and 87%, respectively. The sensitivity of the test was 100% in patients with chronic lymphocytic leukemia and 82% in patients with lymphoma. The diagnostic value of PBGD determinations was shown in a prospective study of a group of patients evaluated because of fever of unknown origin, anemia, or other constitutional symptoms with or without lymphadenopathy or a mediastinal mass. The positive and negative predictive values in these patients were 91% and 100%, respectively. Nearly all patients who were in remission had normal enzyme activity. Lymphocyte PBGD determinations also may be of value in determining when to terminate or reinitiate drug treatment. (<i>JAMA</i>1987;257:39-42)" @default.
- W4300892004 created "2022-10-04" @default.
- W4300892004 creator A5071070425 @default.
- W4300892004 date "1987-01-02" @default.
- W4300892004 modified "2023-10-14" @default.
- W4300892004 title "Increased Porphobilinogen Deaminase Activity in Patients With Malignant Lymphoproliferative Diseases" @default.
- W4300892004 doi "https://doi.org/10.1001/jama.1987.03390010043025" @default.
- W4300892004 hasPublicationYear "1987" @default.
- W4300892004 type Work @default.
- W4300892004 citedByCount "10" @default.
- W4300892004 crossrefType "journal-article" @default.
- W4300892004 hasAuthorship W4300892004A5071070425 @default.
- W4300892004 hasConcept C126322002 @default.
- W4300892004 hasConcept C203014093 @default.
- W4300892004 hasConcept C2776995267 @default.
- W4300892004 hasConcept C2777938653 @default.
- W4300892004 hasConcept C2777940757 @default.
- W4300892004 hasConcept C2778461978 @default.
- W4300892004 hasConcept C2778503633 @default.
- W4300892004 hasConcept C2779028619 @default.
- W4300892004 hasConcept C2779338263 @default.
- W4300892004 hasConcept C71924100 @default.
- W4300892004 hasConcept C90924648 @default.
- W4300892004 hasConceptScore W4300892004C126322002 @default.
- W4300892004 hasConceptScore W4300892004C203014093 @default.
- W4300892004 hasConceptScore W4300892004C2776995267 @default.
- W4300892004 hasConceptScore W4300892004C2777938653 @default.
- W4300892004 hasConceptScore W4300892004C2777940757 @default.
- W4300892004 hasConceptScore W4300892004C2778461978 @default.
- W4300892004 hasConceptScore W4300892004C2778503633 @default.
- W4300892004 hasConceptScore W4300892004C2779028619 @default.
- W4300892004 hasConceptScore W4300892004C2779338263 @default.
- W4300892004 hasConceptScore W4300892004C71924100 @default.
- W4300892004 hasConceptScore W4300892004C90924648 @default.
- W4300892004 hasIssue "1" @default.
- W4300892004 hasLocation W43008920041 @default.
- W4300892004 hasOpenAccess W4300892004 @default.
- W4300892004 hasPrimaryLocation W43008920041 @default.
- W4300892004 hasRelatedWork W1518006666 @default.
- W4300892004 hasRelatedWork W168562638 @default.
- W4300892004 hasRelatedWork W1970042929 @default.
- W4300892004 hasRelatedWork W1997711972 @default.
- W4300892004 hasRelatedWork W2067073543 @default.
- W4300892004 hasRelatedWork W2127803212 @default.
- W4300892004 hasRelatedWork W2358268857 @default.
- W4300892004 hasRelatedWork W2528051186 @default.
- W4300892004 hasRelatedWork W2991737307 @default.
- W4300892004 hasRelatedWork W4240539558 @default.
- W4300892004 hasVolume "257" @default.
- W4300892004 isParatext "false" @default.
- W4300892004 isRetracted "false" @default.
- W4300892004 workType "article" @default.