Matches in SemOpenAlex for { <https://semopenalex.org/work/W4300979751> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4300979751 endingPage "1526" @default.
- W4300979751 startingPage "1517" @default.
- W4300979751 abstract "<h3>BACKGROUND:</h3> Patients hospitalized for COPD exacerbation have an increased risk of mortality, particularly among those who fail bi-level positive airway pressure (BPAP) for hypercapnic respiratory failure subsequently requiring invasive mechanical ventilation. Therefore, we sought to investigate the treatment course of BPAP and factors associated with BPAP treatment failure. <h3>METHODS:</h3> We performed a retrospective cohort study using real-world evidence to investigate subjects with COPD who were treated with BPAP during a hospitalization for COPD exacerbation. Treatment outcomes were defined within 7 d from BPAP initiation as either failure, persistent, or success. Failure was defined as death or progression to invasive ventilation. Persistent was defined as receiving BPAP during hospital day 7. Success was defined as liberation from BPAP prior to hospital day 7 and not meeting criteria for failure. Unadjusted multinomial logistic regression models were used to examine the association between BPAP treatment outcomes and 17 recipient characteristics. <h3>RESULTS:</h3> Among the 427 clinical encounters, 78% were successful, 10% were persistent, and 12% experienced failure. The median time to failure and success was 8 h and 16 h, respectively. Increasing age, body mass index (BMI), bicarbonate level, and creatinine level were significantly associated with either BPAP treatment failure, persistent treatment, or both. <h3>CONCLUSIONS:</h3> The first 8 h following initiation of BPAP is a critical time period where patients are at high risk for life-threatening decompensation. Careful consideration should be given to increasing age, BMI, bicarbonate level, and creatinine level as these factors were associated with BPAP treatment failure or persistent treatment." @default.
- W4300979751 created "2022-10-04" @default.
- W4300979751 creator A5006257570 @default.
- W4300979751 creator A5007605347 @default.
- W4300979751 creator A5021843102 @default.
- W4300979751 creator A5033011383 @default.
- W4300979751 creator A5065327993 @default.
- W4300979751 creator A5085761603 @default.
- W4300979751 date "2022-10-04" @default.
- W4300979751 modified "2023-09-23" @default.
- W4300979751 title "Timing of Treatment Outcomes and Risk Factors for Failure of BPAP in Patients Hospitalized for COPD Exacerbation" @default.
- W4300979751 cites W1234751227 @default.
- W4300979751 cites W1513829807 @default.
- W4300979751 cites W1580757800 @default.
- W4300979751 cites W2015022520 @default.
- W4300979751 cites W2021991057 @default.
- W4300979751 cites W2031232522 @default.
- W4300979751 cites W2039488343 @default.
- W4300979751 cites W2041987026 @default.
- W4300979751 cites W2069273684 @default.
- W4300979751 cites W2075248556 @default.
- W4300979751 cites W2089921985 @default.
- W4300979751 cites W2107371157 @default.
- W4300979751 cites W2114225012 @default.
- W4300979751 cites W2124129697 @default.
- W4300979751 cites W2132217523 @default.
- W4300979751 cites W2141692123 @default.
- W4300979751 cites W2162360797 @default.
- W4300979751 cites W2329899462 @default.
- W4300979751 cites W2462715422 @default.
- W4300979751 cites W2491609588 @default.
- W4300979751 cites W2604501983 @default.
- W4300979751 cites W2736149543 @default.
- W4300979751 cites W2746473595 @default.
- W4300979751 cites W2966600665 @default.
- W4300979751 cites W2976564058 @default.
- W4300979751 cites W3049105089 @default.
- W4300979751 cites W3092917779 @default.
- W4300979751 cites W4210985264 @default.
- W4300979751 doi "https://doi.org/10.4187/respcare.10155" @default.
- W4300979751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36195347" @default.
- W4300979751 hasPublicationYear "2022" @default.
- W4300979751 type Work @default.
- W4300979751 citedByCount "3" @default.
- W4300979751 countsByYear W43009797512022 @default.
- W4300979751 countsByYear W43009797512023 @default.
- W4300979751 crossrefType "journal-article" @default.
- W4300979751 hasAuthorship W4300979751A5006257570 @default.
- W4300979751 hasAuthorship W4300979751A5007605347 @default.
- W4300979751 hasAuthorship W4300979751A5021843102 @default.
- W4300979751 hasAuthorship W4300979751A5033011383 @default.
- W4300979751 hasAuthorship W4300979751A5065327993 @default.
- W4300979751 hasAuthorship W4300979751A5085761603 @default.
- W4300979751 hasConcept C126322002 @default.
- W4300979751 hasConcept C167135981 @default.
- W4300979751 hasConcept C177713679 @default.
- W4300979751 hasConcept C2776780178 @default.
- W4300979751 hasConcept C2776888751 @default.
- W4300979751 hasConcept C2777014857 @default.
- W4300979751 hasConcept C2780221984 @default.
- W4300979751 hasConcept C71924100 @default.
- W4300979751 hasConceptScore W4300979751C126322002 @default.
- W4300979751 hasConceptScore W4300979751C167135981 @default.
- W4300979751 hasConceptScore W4300979751C177713679 @default.
- W4300979751 hasConceptScore W4300979751C2776780178 @default.
- W4300979751 hasConceptScore W4300979751C2776888751 @default.
- W4300979751 hasConceptScore W4300979751C2777014857 @default.
- W4300979751 hasConceptScore W4300979751C2780221984 @default.
- W4300979751 hasConceptScore W4300979751C71924100 @default.
- W4300979751 hasIssue "12" @default.
- W4300979751 hasLocation W43009797511 @default.
- W4300979751 hasLocation W43009797512 @default.
- W4300979751 hasOpenAccess W4300979751 @default.
- W4300979751 hasPrimaryLocation W43009797511 @default.
- W4300979751 hasRelatedWork W1974526650 @default.
- W4300979751 hasRelatedWork W2077638660 @default.
- W4300979751 hasRelatedWork W2110152822 @default.
- W4300979751 hasRelatedWork W2140043130 @default.
- W4300979751 hasRelatedWork W2160736681 @default.
- W4300979751 hasRelatedWork W2230037512 @default.
- W4300979751 hasRelatedWork W2405673156 @default.
- W4300979751 hasRelatedWork W3160337907 @default.
- W4300979751 hasRelatedWork W3184513407 @default.
- W4300979751 hasRelatedWork W2127760953 @default.
- W4300979751 hasVolume "67" @default.
- W4300979751 isParatext "false" @default.
- W4300979751 isRetracted "false" @default.
- W4300979751 workType "article" @default.