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• W4301022995 abstract "Only male zebra finches sing, and several brain regions implicated in song behavior exhibit marked sex differences in neuron number. In one region, the high vocal center (HVC), this dimorphism develops because the incorporation of new neurons is greater in males than in females during the first several weeks after hatching. Although estrogen (E2) exposure stimulates neuron addition in females, it is not known where (E2) acts, or to what extent sexual differentiation influences the production, specification, or survival of HVC neurons. In the present study we first reassessed sex and (E2)-induced differences in cell degeneration within the HVC using the TUNEL technique to identify cells undergoing DNA fragmentation indicative of apoptosis. HVC neuron number, as well as the density and number of TUNEL-labeled and pyknotic cells within the HVC were measured in normal 20- and 30-day-old males and females, and in 30-day-old females implanted with E2 on posthatch day 18. Although HVC neuron number was greater in males than in females, and was masculinized in E2 females, no group differences were evident in the absolute number of dying cells. These results indicate that sex differences in cell survival within the HVC do not entirely account for sexually dimorphic neuron addition to this region. Rather, sexual differentiation acts on some HVC neurons before they complete their migration and/or early differentiation. Although the migratory route of HVC neurons is not known, a large number of E2 receptor-containing cells (ER cells) reside just ventromedial to the HVC and adjacent to the proliferative ventricular zone. Next, we investigated whether these ER cells contribute to early-arising sex differences in HVC neuron addition. By combining [3H] thymidine autoradiography with immunocytochemistry for ERs, we first established that ER-expressing cells are not generated during posthatch sexually dimorphic HVC neuron addition, and thus are not young HVC neurons that transiently express ERs during their migration. Furthermore, in 25-day-old birds we found no sex difference in the density of pyknotic cells among this group of ER cells, suggesting that these cells do not promote the differential survival of HVC neuronal precursors migrating through this region. Rather, ER cells or other cell populations may establish sex differences in HVC neuron number by creating dimorphisms in cellular specification. © 1997 John Wiley & Sons, Inc. J Neurobiol 33: 61–71, 1997" @default.
• W4301022995 created "2022-10-04" @default.
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• W4301022995 date "1997-07-01" @default.
• W4301022995 modified "2023-09-27" @default.
• W4301022995 title "Sexually dimorphic neuron addition to an avian song-control region is not accounted for by sex differences in cell death" @default.
• W4301022995 cites W1559620581 @default.
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• W4301022995 cites W1761997414 @default.
• W4301022995 cites W1892136299 @default.
• W4301022995 cites W1952728589 @default.
• W4301022995 cites W1964607223 @default.
• W4301022995 cites W1970147140 @default.
• W4301022995 cites W1974743245 @default.
• W4301022995 cites W1975829354 @default.
• W4301022995 cites W1976495127 @default.
• W4301022995 cites W1980813865 @default.
• W4301022995 cites W1984832180 @default.
• W4301022995 cites W1989389324 @default.
• W4301022995 cites W1991586771 @default.
• W4301022995 cites W1992056427 @default.
• W4301022995 cites W1993321925 @default.
• W4301022995 cites W1995180942 @default.
• W4301022995 cites W1997447798 @default.
• W4301022995 cites W1999301655 @default.
• W4301022995 cites W2001106917 @default.
• W4301022995 cites W2002673255 @default.
• W4301022995 cites W2002737045 @default.
• W4301022995 cites W2005948567 @default.
• W4301022995 cites W2012166019 @default.
• W4301022995 cites W2012391494 @default.
• W4301022995 cites W2013708119 @default.
• W4301022995 cites W2017032811 @default.
• W4301022995 cites W2017670805 @default.
• W4301022995 cites W2019089683 @default.
• W4301022995 cites W2020477045 @default.
• W4301022995 cites W2020841755 @default.
• W4301022995 cites W2027373710 @default.
• W4301022995 cites W2029106054 @default.
• W4301022995 cites W2030564926 @default.
• W4301022995 cites W2035077777 @default.
• W4301022995 cites W2035871570 @default.
• W4301022995 cites W2036644342 @default.
• W4301022995 cites W2036698042 @default.
• W4301022995 cites W2043466815 @default.
• W4301022995 cites W2051132718 @default.
• W4301022995 cites W2052844486 @default.
• W4301022995 cites W2058479911 @default.
• W4301022995 cites W2060495631 @default.
• W4301022995 cites W2061053248 @default.
• W4301022995 cites W2064377090 @default.
• W4301022995 cites W2070042589 @default.
• W4301022995 cites W2070172938 @default.
• W4301022995 cites W2070759979 @default.
• W4301022995 cites W2079907641 @default.
• W4301022995 cites W2083140708 @default.
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• W4301022995 cites W2085525308 @default.
• W4301022995 cites W2086490228 @default.
• W4301022995 cites W2089616328 @default.
• W4301022995 cites W2099751225 @default.
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• W4301022995 cites W2204303744 @default.
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• W4301022995 doi "https://doi.org/10.1002/(sici)1097-4695(199707)33:1<61::aid-neu6>3.0.co;2-b" @default.
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