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- W4301368712 abstract "The effectiveness and safety of huaier granules in reducing recurrence after curative resection of HCC have been confirmed, but it is unclear whether huaier granules can significantly prolong overall survival.To demonstrate the effectiveness of huaier granule for HCC after curative resection over a 5-year follow-up.A total of 1265 HCC patients who underwent curative resection from January 2008 to January 2020 were enrolled, 1111 patients were finally enrolled according to the exclusion criteria, and the oncology outcome of Huaier granule was analyzed by propensity score matching method (PSM).Before propensity score matching, huaier granule resulted in better 5- year overall survival (61.49% vs 54.92%, p = 0.0099) and recurrence-free survival (45.64% vs 38.42%, p = 0.0042) for HCC patients. For solitary HCC ≤30 mm, huaier granule resulted in similar 5- year recurrence-free survival (54.55% vs 50.13%, p = 0.4403), but better 5- year overall survival (82.42% vs70.08%, p = 0.0189). Similar to overall patients, huaier granule resulted in better 5- year overall survival (54.77% vs 51.37%, p = 0.1530) and recurrence-free survival (42.61% vs 35.62%, p = 0.0082) for solitary HCC >30 mm. After propensity score matching, we did confirm that huaier granules can significantly prolong overall survival by more than 5 years, the exception was recurrence-free survival in the HCC <30 mm cohort." @default.
- W4301368712 created "2022-10-05" @default.
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- W4301368712 date "2023-01-01" @default.
- W4301368712 modified "2023-09-26" @default.
- W4301368712 title "Huaier granule prolongs overall survival after curative resection of hepatocarcinoma carcinoma: A propensity score analysis" @default.
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- W4301368712 doi "https://doi.org/10.1016/j.jep.2022.115774" @default.
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