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- W4301384275 abstract "Biopsy of the developing placenta before the thirteenth gestational week was performed by transcervical cannula aspiration guided by real-time ultrasound in 21 consecutive patients. Chorionic villi were obtained in 20 patients and chromosomal analysis was possible in 19. One significant complication occurred: perforation of one gestational sac in the only patient in the series with a twin pregnancy. More studies are required in order to provide an adequate assessment of the risk – of fetal loss, culture failure and trophoblastic chromosomal abnormalities not representative of the mature fetus — associated with the technique. In practised hands, the procedure may provide a preferable and safe alternative to amniocentesis and fetoscopy for the prenatal diagnosis of genetic defects." @default.
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- W4301384275 date "1985-03-01" @default.
- W4301384275 modified "2023-09-26" @default.
- W4301384275 title "Prenatal diagnosis: A preliminary study of first‐trimester chorionic villous biopsy" @default.
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- W4301384275 doi "https://doi.org/10.5694/j.1326-5377.1985.tb113366.x" @default.
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