FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4301401064> ?p ?o ?g. }

• W4301401064 endingPage "4021" @default.
• W4301401064 startingPage "4019" @default.
• W4301401064 abstract "Cyanobacteria thrive near the surface of their aquatic environment, where a rich mixture of carbon dioxide, water, and sunlight produces the optimal conditions for photosynthesis. These microorganisms regulate their buoyancy by producing rigid, cylindrical gas vesicles (GVs), granting them mobility in the water column ( 1 Walsby A.E. Gas vesicles. Microbiol. Rev. 1994; 58: 94-144 Crossref PubMed Google Scholar ). Like any pressure vessel, there is a threshold pressure difference between the internal and surrounding media, beyond which the GVs will break. Naturally, the proteinaceous structures found in cyanobacteria and several archaea have evolved to endure the hydrostatic pressure of their environment ( 1 Walsby A.E. Gas vesicles. Microbiol. Rev. 1994; 58: 94-144 Crossref PubMed Google Scholar ). The exceptional stability of GVs is partly attributed to beta-sheet structures formed by the self-assembly of GV subunits. This results in a highly ordered protein shell that exhibits Young’s moduli comparable to glassy polymers (a few GPas). When the threshold or critical pressure is surpassed and the vesicles rupture, they disappear under a light microscope. This dramatic change in optical properties due to rupture was the first example of GV use as a signaling agent, operating as a pressure gauge in this case. Further characterization of GV geometry and composition as well as the invention of high-resolution optical and acoustic imaging tools like electron microscopy, NMR, and ultrasound imaging has expanded the possible use cases for GVs as sensors and reporters. Although assembly of the gas-permeable membrane is a complex process requiring a cluster of 14 genes, the vesicle membrane itself is constructed from just two proteins. The alpha-helical hydrophilic protein GvpC forms rod-like reinforcements over the smaller, beta-sheet-forming hydrophobic protein GvpA, generating a membrane that promotes gas transport, inhibits water permeation, and is mechanically robust despite being roughly a couple of nanometers thick. Accurate measurement of GV dimensions is critical for predicting rupture pressure and signal calibration. The size distributions of GVs from some of the most commonly studied species have been approximated using multiple techniques, but most recently, Dutka et al. demonstrated that cryogenic electron microscopy (cryo-EM) preserves morphology better for dimensional characterization than other forms of electron microscopy ( 2 Dutka P. Malounda D. Shapiro M.G. et al. Measuring gas vesicle dimensions by electron microscopy. Protein Sci. 2021; 30: 1081-1086 Crossref PubMed Scopus (9) Google Scholar ). The exceptional structural details of GVs revealed by cryo-EM paves the way for further understanding of the role of geometry on the physics of these systems, for instance by molecular dynamics simulations and other structural analysis methods." @default.
• W4301401064 created "2022-10-05" @default.
• W4301401064 creator A5014744105 @default.
• W4301401064 creator A5024800811 @default.
• W4301401064 date "2022-11-01" @default.
• W4301401064 modified "2023-09-28" @default.
• W4301401064 title "Bacterial flotation devices enhance ultrasound imaging" @default.
• W4301401064 cites W2026988376 @default.
• W4301401064 cites W2106322681 @default.
• W4301401064 cites W2352585650 @default.
• W4301401064 cites W2765468199 @default.
• W4301401064 cites W2975580645 @default.
• W4301401064 cites W3135814287 @default.
• W4301401064 cites W3198054686 @default.
• W4301401064 cites W4211151288 @default.
• W4301401064 cites W4295015156 @default.
• W4301401064 doi "https://doi.org/10.1016/j.bpj.2022.10.004" @default.
• W4301401064 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36257324" @default.
• W4301401064 hasPublicationYear "2022" @default.
• W4301401064 type Work @default.
• W4301401064 citedByCount "0" @default.
• W4301401064 crossrefType "journal-article" @default.
• W4301401064 hasAuthorship W4301401064A5014744105 @default.
• W4301401064 hasAuthorship W4301401064A5024800811 @default.
• W4301401064 hasConcept C121332964 @default.
• W4301401064 hasConcept C12554922 @default.
• W4301401064 hasConcept C130316041 @default.
• W4301401064 hasConcept C157915830 @default.
• W4301401064 hasConcept C171250308 @default.
• W4301401064 hasConcept C185592680 @default.
• W4301401064 hasConcept C192562407 @default.
• W4301401064 hasConcept C2910081258 @default.
• W4301401064 hasConcept C41625074 @default.
• W4301401064 hasConcept C538625479 @default.
• W4301401064 hasConcept C55493867 @default.
• W4301401064 hasConcept C57879066 @default.
• W4301401064 hasConcept C62520636 @default.
• W4301401064 hasConcept C86803240 @default.
• W4301401064 hasConcept C97355855 @default.
• W4301401064 hasConceptScore W4301401064C121332964 @default.
• W4301401064 hasConceptScore W4301401064C12554922 @default.
• W4301401064 hasConceptScore W4301401064C130316041 @default.
• W4301401064 hasConceptScore W4301401064C157915830 @default.
• W4301401064 hasConceptScore W4301401064C171250308 @default.
• W4301401064 hasConceptScore W4301401064C185592680 @default.
• W4301401064 hasConceptScore W4301401064C192562407 @default.
• W4301401064 hasConceptScore W4301401064C2910081258 @default.
• W4301401064 hasConceptScore W4301401064C41625074 @default.
• W4301401064 hasConceptScore W4301401064C538625479 @default.
• W4301401064 hasConceptScore W4301401064C55493867 @default.
• W4301401064 hasConceptScore W4301401064C57879066 @default.
• W4301401064 hasConceptScore W4301401064C62520636 @default.
• W4301401064 hasConceptScore W4301401064C86803240 @default.
• W4301401064 hasConceptScore W4301401064C97355855 @default.
• W4301401064 hasFunder F4320306076 @default.
• W4301401064 hasFunder F4320309475 @default.
• W4301401064 hasIssue "21" @default.
• W4301401064 hasLocation W43014010641 @default.
• W4301401064 hasLocation W43014010642 @default.
• W4301401064 hasOpenAccess W4301401064 @default.
• W4301401064 hasPrimaryLocation W43014010641 @default.
• W4301401064 hasRelatedWork W2000765671 @default.
• W4301401064 hasRelatedWork W2057334135 @default.
• W4301401064 hasRelatedWork W2075228146 @default.
• W4301401064 hasRelatedWork W2089175216 @default.
• W4301401064 hasRelatedWork W2094438117 @default.
• W4301401064 hasRelatedWork W2602501348 @default.
• W4301401064 hasRelatedWork W2608936667 @default.
• W4301401064 hasRelatedWork W2899084033 @default.
• W4301401064 hasRelatedWork W4200061308 @default.
• W4301401064 hasRelatedWork W4304608978 @default.
• W4301401064 hasVolume "121" @default.
• W4301401064 isParatext "false" @default.
• W4301401064 isRetracted "false" @default.
• W4301401064 workType "article" @default.