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- W4301453553 abstract "A well-documented but uncommon side effect of minocycline hydrochloride therapy is mucocutaneous pigmentation.<sup>1</sup>Although the exact nature of the pigment deposited is still controversial, melanin and iron appear to play important roles in creating the blue-gray discoloration.<sup>2</sup>Treatment for the complication has traditionally been cessation of drug use. We report the effective use of the Q-switched ruby laser in eliminating a case of minocycline-induced hyperpigmentation. <h3>Report of a Case.</h3> A 69-year-old man with a long history of rosacea began oral minocycline hydrochloride therapy (100 mg twice a day) in 1993. In April 1995, he presented with profound blue-gray pigmentation over the forehead, temporal area, preauricular area, and upper part of the cheeks. Small (<1 cm) blue-gray macules were also found on his shins. His sclera and teeth were spared. Three areas on the shins were chosen for a therapeutic trial with lasers. A biopsy was performed on l" @default.
- W4301453553 created "2022-10-05" @default.
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- W4301453553 date "1996-10-01" @default.
- W4301453553 modified "2023-10-18" @default.
- W4301453553 title "Treatment of Minocycline-Induced Hyperpigmentation With the Q-Switched Ruby Laser" @default.
- W4301453553 doi "https://doi.org/10.1001/archderm.1996.03890340116025" @default.
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